Oxiranecarboxylic acid, 2-(1-hydroxyethyl)-, ethyl ester, (R*,S*)- (9CI)

Base Information

• Chemical Name: Oxiranecarboxylic acid, 2-(1-hydroxyethyl)-, ethyl ester, (R*,S*)- (9CI)
• CAS No.: 100841-15-4
• Molecular Formula: C₇H₁₂O₄
• Molecular Weight: 160.17
• Mol file: 100841-15-4.mol

Synonyms:Oxiranecarboxylic acid, 2-(1-hydroxyethyl)-, ethyl ester, (R*,S*)- (9CI)

Chemical Property of Oxiranecarboxylic acid, 2-(1-hydroxyethyl)-, ethyl ester, (R*,S*)- (9CI)

Chemical Property:

• PSA: 59.06000
• LogP: -0.30070

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxiranecarboxylic acid, 2-(1-hydroxyethyl)-, ethyl ester, (R*,S*)- (9CI)

There total 10 articles about Oxiranecarboxylic acid, 2-(1-hydroxyethyl)-, ethyl ester, (R*,S*)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

ethyl 3-hydroxy-2-methylenebutanoate (98837-34-4,130196-00-8,19362-99-3) → (R*,S*)-2-(1-Hydroxyethyl)oxiranecarboxylate (100841-15-4)

Guidance literature:

With tert.-butylhydroperoxide; bis(acetylacetonate)oxovanadium; In dichloromethane; benzene; for 5h; Heating;

DOI:10.1021/ja00183a032

Reference yield: 68.0%

Ethyl tiglate (5837-78-5,55514-48-2) → ethyl 3-hydroxy-2-methylenebutanoate (98837-34-4,130196-00-8,19362-99-3) + 2-(1-Hydroxy-ethyl)-oxirane-2-carboxylic acid ethyl ester (100841-15-4,100858-09-1)

Guidance literature:

With titanium(IV) isopropylate; oxygen; 5,15,10,20-tetraphenylporphyrin; In dichloromethane; at 0 ℃; Irradiation;

DOI:10.1016/S0040-4039(00)84656-0

Reference yield: 68.0%

ethyl 3-hydroperoxy-2-methylenebutanoate (100841-11-0) → ethyl 3-hydroxy-2-methylenebutanoate (98837-34-4,130196-00-8,19362-99-3) + (R)-2-((S)-1-Hydroxy-ethyl)-oxirane-2-carboxylic acid ethyl ester (100841-15-4,100858-09-1)

Guidance literature:

With titanium(IV) isopropylate; In dichloromethane; at 0 ℃; Title compound not separated from byproducts;

upstream raw materials:

Ethyl tiglate

ethyl 3-hydroxy-2-methylenebutanoate

ethyl 3-hydroperoxy-2-methylenebutanoate