2-formyl-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene

Base Information

• Chemical Name: 2-formyl-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene
• CAS No.: 392657-76-0
• Molecular Formula: C₁₇H₁₇NO₃S
• Molecular Weight: 315.393
• Mol file: 392657-76-0.mol

Synonyms:2-formyl-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene

Chemical Property of 2-formyl-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-formyl-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene

There total 1 articles about 2-formyl-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 2-[(4-N,N-dimethylaminobenzylidene)methyl]-3,4-ethylenedioxythiophene → 2-formyl-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene (392657-76-0)

Guidance literature:

With trichlorophosphate; In 1,2-dichloro-ethane; for 2h; Heating;

DOI:10.1021/jo010713f

Reference yield: 71.0%

3-(1,1-dicyanomethylene)-indanone (1080-74-6) + 2-formyl-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene (392657-76-0) → 2-(3-dicyanomethylidene-1-indanon-2-ylidenemethyl)-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene

Guidance literature:

In ethanol; at 60 - 70 ℃; for 0.5h;

DOI:10.1021/jo010713f

Reference yield: 55.0%

1,3-bis(dicyanomethylidene)-indane (38172-19-9) + 2-formyl-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene (392657-76-0) → 2-[1,3-bis(dicyanomethylidene)indan-2-ylidenemethyl]-3,4-ethylenedioxy-5-[(E)-(4-N,N-dimethylaminobenzylidene)methyl]thiophene

Guidance literature:

In acetic anhydride; at 60 - 70 ℃; for 1h;

DOI:10.1021/jo010713f

upstream raw materials:

N,N-dimethyl-formamide