N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide

Base Information

Chemical Name:N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide
CAS No.:96896-83-2
Molecular Formula:C₁₉H₂₁N₃O₄
Molecular Weight:355.393
Hs Code.:

Synonyms:N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide

Suppliers and Price of N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide

There total 4 articles about N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 96866-09-0
N-<2(RS)-<(benzyloxyamino)carbonyl>-1-oxo-3-phenylpropyl>glycine benzylamide

: 96896-83-2
N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 3h; Ambient temperature;
DOI:10.1021/jm00147a007

Reference yield:

: 2985-39-9,175521-78-5
2-benzylmalonic acid monoethyl ester

: 96896-83-2
N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / Et₃N, 1-hydroxybenzotriazole (HOBt), DCC / tetrahydrofuran; CHCl₃ / Ambient temperature

2: 64 percent / 2.5 N aq. NaOH / methanol / 4 h / Ambient temperature

3: 88 percent / Et₃N, 1-hydroxybenzotriazol (HOBT), N-cyclohexyl-N'-<2-(4-morpholinyl)ethyl>carbodiimide methol p-toluenosulfonate / tetrahydrofuran / Ambient temperature

4: 93 percent / H₂ / 10percent Pd on charcoal / methanol / 3 h / Ambient temperature

With sodium hydroxide; hydrogen; N-cyclohexyl-N'-β-(4-methylmorpholinium)ethylcarbodiimide p-toluenesulfonate; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; methanol; chloroform;
DOI:10.1021/jm00147a007

Reference yield:

: 67681-99-6
α-[(benzyloxy)carbamoyl]hydrocinnamic acid

: 96896-83-2
N-{2(RS)-[(hydroxyamino)carbonyl]-1-oxo-3-phenylpropyl}glycine benzylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / Et₃N, 1-hydroxybenzotriazol (HOBT), N-cyclohexyl-N'-<2-(4-morpholinyl)ethyl>carbodiimide methol p-toluenosulfonate / tetrahydrofuran / Ambient temperature

2: 93 percent / H₂ / 10percent Pd on charcoal / methanol / 3 h / Ambient temperature

With hydrogen; N-cyclohexyl-N'-β-(4-methylmorpholinium)ethylcarbodiimide p-toluenesulfonate; benzotriazol-1-ol; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1021/jm00147a007