[(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate

Base Information

• Chemical Name: [(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate
• CAS No.: 936644-41-6
• Molecular Formula: C₂₃H₂₈N₂O₄S
• Molecular Weight: 428.552

Synonyms:[(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate

Chemical Property of [(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate

There total 2 articles about [(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

but-3-yne-1-sulfonic acid ((R,R)-2-amino-1,2-diphenylethyl)-amide (936644-40-5) + di-tert-butyl dicarbonate (24424-99-5) → [(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate (936644-41-6)

Guidance literature:

In tetrahydrofuran; at 20 ℃;

DOI:10.1039/b700744b

Reference yield:

(R,R)-1,2-diphenylethylenediamine (35132-20-8) → [(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate (936644-41-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 62 percent / triethylamine / CH₂Cl₂ / 0 - 20 °C

2: 97 percent / tetrahydrofuran / 20 °C

With triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1039/b700744b

Reference yield:

[(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate (936644-41-6) + 4,4-dimethyl-3-methylenepent-1-ene (2495-32-1) → C26H34SO2N2 + C26H34SO2N2

Guidance literature:

[(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate; 4,4-dimethyl-3-methylenepent-1-ene; [Rh(cycloocta-1,5-diene)(naphthalene)]BF₄; In dichloromethane; at 20 ℃; for 2h;

With hydrogenchloride; In diethyl ether; dichloromethane; at 20 ℃; Further stages. Title compound not separated from byproducts.;

DOI:10.1039/b700744b

upstream raw materials:

but-3-yne-1-sulfonic acid ((R,R)-2-amino-1,2-diphenylethyl)-amide

di-tert-butyl dicarbonate

(R,R)-1,2-diphenylethylenediamine

Downstream raw materials:

{(R,R)-2-[2-(4-tert-butylcyclohexa-1,4-dienyl)-ethanesulfonylamino]-1,2-diphenylethyl}-tert-butyl carbamate

{(R,R)-2-[2-(4-adamantan-1-ylcyclohexa-1,4-dienyl)-ethanesulfonylamino]-1,2-diphenylethyl}-tert-butyl carbamate

{(R,R)-1,2-diphenyl-2-[2-(4-phenylcyclohexa-1,4-dienyl)-ethanesulfonylamino]-ethyl}-tert-butyl carbamate

{(R,R)-2-[2-(4-methylcyclohexa-1,4-dienyl)-ethanesulfonylamino]-1,2-diphenylethyl} tert-butyl carbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 936644-41-6 [(R,R)-2-(but-3-yne-1-sulfonylamino)-1,2-diphenylethyl]-tert-butyl carbamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send