3-fluoro-3-phenyl-1-heptene

Base Information

Chemical Name:3-fluoro-3-phenyl-1-heptene
CAS No.:1407518-47-1
Molecular Formula:C₁₃H₁₇F
Molecular Weight:192.276
Hs Code.:

Synonyms:3-fluoro-3-phenyl-1-heptene

Suppliers and Price of 3-fluoro-3-phenyl-1-heptene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3-fluoro-3-phenyl-1-heptene

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 3-fluoro-3-phenyl-1-heptene

There total 6 articles about 3-fluoro-3-phenyl-1-heptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 693-03-8
n-butyl magnesium bromide

: 1407518-30-2
diethyl (2Z)-3-fluoro-3-phenylprop-2-en-1-yl phosphate

: 1407518-47-1
3-fluoro-3-phenyl-1-heptene

Guidance literature:: n-butyl magnesium bromide; With copper(l) cyanide; In tetrahydrofuran; at -78 - -10 ℃; for 0.333333h; Inert atmosphere;

diethyl (2Z)-3-fluoro-3-phenylprop-2-en-1-yl phosphate; In tetrahydrofuran; at -40 ℃; for 0.5h; Temperature; Reagent/catalyst; Concentration; regioselective reaction; Inert atmosphere;
DOI:10.1039/c2ob25718a

Reference yield:

: 693-03-8
n-butyl magnesium bromide

: 1407518-30-2
diethyl (2Z)-3-fluoro-3-phenylprop-2-en-1-yl phosphate

: 1407518-47-1
3-fluoro-3-phenyl-1-heptene

: 1407518-44-8
C₁₃H₁₇F

Guidance literature:: n-butyl magnesium bromide; With copper(l) cyanide; In tetrahydrofuran; at -78 - -10 ℃; for 0.333333h; Inert atmosphere;

diethyl (2Z)-3-fluoro-3-phenylprop-2-en-1-yl phosphate; In tetrahydrofuran; at -40 ℃; for 0.5h; Temperature; Reagent/catalyst; Concentration; Overall yield = 43 %; regioselective reaction; Inert atmosphere;
DOI:10.1039/c2ob25718a

Reference yield:

: 105304-62-9
ethyl (2Z)-3-fluoro-3-phenylprop-2-enoate

: 1407518-47-1
3-fluoro-3-phenyl-1-heptene

Guidance literature:: Multi-step reaction with 3 steps

1.1: diisobutylaluminium hydride / dichloromethane; hexane / 0.5 h / 0 °C / Inert atmosphere

2.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

3.1: copper(l) cyanide / tetrahydrofuran / 0.33 h / -78 - -10 °C / Inert atmosphere

3.2: 0.5 h / -40 °C / Inert atmosphere

With dmap; copper(l) cyanide; diisobutylaluminium hydride; triethylamine; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1039/c2ob25718a