(4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one

Base Information

Chemical Name:(4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one
CAS No.:138433-75-7
Molecular Formula:C₂₁H₂₆O₄Si
Molecular Weight:370.521
Hs Code.:

Synonyms:(4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one

Suppliers and Price of (4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one

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Technology Process of (4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one

There total 7 articles about (4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 138433-69-9
5-O-(tert-butyldiphenylsilyl)-3-O-benzyl-2-deoxy-D-ribonolactone

: 138433-75-7
(4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; In methanol; acetone; for 72h; under 2585.7 Torr; Ambient temperature;

Reference yield: 78.0%

: 58479-61-1
tert-butylchlorodiphenylsilane

: 34371-14-7
2-deoxy-D-ribonolactone

: 138433-75-7
(4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one

Guidance literature:: With pyridine; for 12h; Ambient temperature;

Reference yield:

: 128111-92-2
(2S,3R)-2-<3,4-O-isopropylidene-2,3,4-trihydroxybut-1-yl>-1,3-dithiane

: 138433-75-7
(4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-4-hydroxydihydrofuran-2(3H)-one

Guidance literature:: Multi-step reaction with 6 steps

1: 96 percent / dimethylformamide

2: 99 percent / 10percent aq. HCl / tetrahydrofuran / 4 h / Ambient temperature

3: 93 percent / DMAP, pyridine / CH₂Cl₂ / 24 h / Ambient temperature

4: 90 percent / CH₃I, CaCO₃, water / acetonitrile / 20 h / 47 °C

5: 93 percent / tetrapropylammonium perruthenate, 4-methylmorpholine N-oxide, 4 A sieves / CH₂Cl₂ / 4 h / Ambient temperature

6: 80 percent / H₂, acetic acid / 10percent Pd/C / acetone; methanol / 72 h / 2585.7 Torr / Ambient temperature

With pyridine; hydrogenchloride; dmap; tetrapropylammonium perruthennate; 4 A molecular sieve; water; hydrogen; acetic acid; 4-methylmorpholine N-oxide; calcium carbonate; methyl iodide; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetone; acetonitrile;