(6S)-N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-methyl-4-oxo-5-methyl-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (S)-1-phenylethylamine salt

Base Information

• Chemical Name: (6S)-N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-methyl-4-oxo-5-methyl-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (S)-1-phenylethylamine salt
• CAS No.: 1184180-70-8
• Molecular Formula: C₈H₁₁N*C₂₀H₂₅N₇O₆
• Molecular Weight: 580.644

Synonyms:(6S)-N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-methyl-4-oxo-5-methyl-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (S)-1-phenylethylamine salt

Chemical Property of (6S)-N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-methyl-4-oxo-5-methyl-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (S)-1-phenylethylamine salt

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Technology Process of (6S)-N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-methyl-4-oxo-5-methyl-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (S)-1-phenylethylamine salt

There total 1 articles about (6S)-N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-methyl-4-oxo-5-methyl-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (S)-1-phenylethylamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-phenyl-ethylamine (2627-86-3) + N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (76937-22-9) → (6S)-N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-methyl-4-oxo-5-methyl-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (S)-1-phenylethylamine salt (1184180-70-8)

Guidance literature:

In water; at 0 - 60 ℃; Inert atmosphere;

Reference yield:

(6S)-N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-methyl-4-oxo-5-methyl-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (S)-1-phenylethylamine salt (1184180-70-8) → (6S)-N[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-5-methyl-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid (76937-22-9)

Guidance literature:

With hydrogenchloride; In water; at 0 ℃; pH=3; Inert atmosphere;

upstream raw materials:

(S)-1-phenyl-ethylamine

N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

Downstream raw materials:

(6S)-N[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-5-methyl-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

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