2-benzyl-1H-benzo[f]isoindole-1,3(2H)-dione

Base Information

• Chemical Name: 2-benzyl-1H-benzo[f]isoindole-1,3(2H)-dione
• CAS No.: 20013-26-7
• Molecular Formula: C₁₉H₁₃NO₂
• Molecular Weight: 287.318
• Mol file: 20013-26-7.mol

Synonyms:2-benzyl-1H-benzo[f]isoindole-1,3(2H)-dione

Chemical Property of 2-benzyl-1H-benzo[f]isoindole-1,3(2H)-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzyl-1H-benzo[f]isoindole-1,3(2H)-dione

There total 2 articles about 2-benzyl-1H-benzo[f]isoindole-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2,3-Naphthalenedicarboxylic anhydride (716-39-2) + benzylamine (100-46-9) → 2-benzyl-1H-benzo[f]isoindole-1,3(2H)-dione (20013-26-7)

Guidance literature:

With acetic acid; at 120 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.8b02287

Reference yield:

→ 2-benzyl-1H-benzo[f]isoindole-1,3(2H)-dione (20013-26-7)

Guidance literature:

Naphthalin-2,3-dicarbonsaeure-di-N-benzyl-amid, in CF3COOD, 8 Monate;

DOI:10.1021/jo01260a035

Reference yield: 61.0%

2-benzyl-1H-benzo[f]isoindole-1,3(2H)-dione (20013-26-7) → 3-phenylbenzo[g]isoquinoline (1072066-63-7)

Guidance literature:

With diethoxymethylane; potassium trimethylsilonate; In diethylene glycol dimethyl ether; at 120 ℃; for 6h; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.8b02287

upstream raw materials:

2,3-Naphthalenedicarboxylic anhydride

benzylamine

Downstream raw materials:

3-phenylbenzo[g]isoquinoline

Refernces

• 1、 Wu, Xiaoyu,Ding, Guangni,Yang, Liqun,Lu, Wenkui,Li, Wanfang,Zhang, Zhaoguo,Xie, Xiaomin. "Alkoxide-Catalyzed Hydrosilylation of Cyclic Imides to Isoquinolines via Tandem Reduction and Rearrangement". supporting information. p. 5610 - 5613. Retrieved 2018/09/12.