N-(5-methyl-4-isoxazolyl)acetamide

Base Information

Chemical Name:N-(5-methyl-4-isoxazolyl)acetamide
CAS No.:100499-63-6
Molecular Formula:C6H8 N2 O2
Molecular Weight:140.13992
Hs Code.:
DSSTox Substance ID:DTXSID80541901
Wikidata:Q82418368
Mol file:100499-63-6.mol

Synonyms:N-(5-methyl-4-isoxazolyl)acetamide;100499-63-6;N-(5-methyl-1,2-oxazol-4-yl)acetamide;SCHEMBL11016941;DTXSID80541901;N-(5-Methylisoxazol-4-yl)acetamide;AKOS006332455

Suppliers and Price of N-(5-methyl-4-isoxazolyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(5-METHYL-4-ISOXAZOLYL)ACETAMIDE 95.00%
5MG
$ 501.18

Total 2 raw suppliers

Chemical Property of N-(5-methyl-4-isoxazolyl)acetamide

Chemical Property:

Vapor Pressure:0.000207mmHg at 25°C
Refractive Index:1.534
Boiling Point:327.1°C at 760 mmHg
Flash Point:151.6°C
PSA：55.13000
Density:1.22g/cm³
LogP:1.01440
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:140.058577502
Heavy Atom Count:10
Complexity:138

Purity/Quality:

95% ^*data from raw suppliers

N-(5-METHYL-4-ISOXAZOLYL)ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=NO1)NC(=O)C

Technology Process of N-(5-methyl-4-isoxazolyl)acetamide

There total 2 articles about N-(5-methyl-4-isoxazolyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 100499-66-9
5-methylisoxazole-4-amine hydrochloride

: 108-24-7
acetic anhydride

: 100499-63-6
N-(5-methyl-4-isoxazolyl)acetamide

Guidance literature:: With sodium acetate; acetic acid; at 20 ℃; for 18h;
DOI:10.1016/j.bmcl.2008.09.024

Reference yield:

: 100499-63-6
N-(5-methyl-4-isoxazolyl)acetamide

Guidance literature:

Reference yield:

: 100499-63-6
N-(5-methyl-4-isoxazolyl)acetamide

: 92007-22-2
4-acetyl-1-benzyl-2-methylimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / H₂ / 10percent Pd on C / methanol / 1 h / 2327.2 Torr / Ambient temperature

2: NaOH / ethanol / 1 h / Heating

3: 1.) NaH / 1.) THF, RT, 20 min, 2.) THF, reflux, 16 h

With sodium hydroxide; hydrogen; sodium hydride; palladium on activated charcoal; In methanol; ethanol;
DOI:10.1021/jo00389a015