N-[morpholin-4-yl(oxido)phenyl-l6-sulfanylidene]-2-(trimethylsilyl)ethanesulfonamide

Base Information

• Chemical Name: N-[morpholin-4-yl(oxido)phenyl-l6-sulfanylidene]-2-(trimethylsilyl)ethanesulfonamide
• CAS No.: 1394013-32-1
• Molecular Formula: C₁₅H₂₆N₂O₄S₂Si
• Molecular Weight: 390.6
• Mol file: 1394013-32-1.mol

Synonyms:N-[morpholin-4-yl(oxido)phenyl-l6-sulfanylidene]-2-(trimethylsilyl)ethanesulfonamide

Chemical Property of N-[morpholin-4-yl(oxido)phenyl-l6-sulfanylidene]-2-(trimethylsilyl)ethanesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[morpholin-4-yl(oxido)phenyl-l6-sulfanylidene]-2-(trimethylsilyl)ethanesulfonamide

There total 2 articles about N-[morpholin-4-yl(oxido)phenyl-l6-sulfanylidene]-2-(trimethylsilyl)ethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

morpholine (110-91-8,99108-56-2) + C11H18ClNO3S2Si → N-[morpholin-4-yl(oxido)phenyl-l6-sulfanylidene]-2-(trimethylsilyl)ethanesulfonamide (1394013-32-1)

Guidance literature:

In acetonitrile; at 20 ℃;

DOI:10.1016/j.tet.2012.06.072

Reference yield:

benzenesulphinyl chloride (4972-29-6) → N-[morpholin-4-yl(oxido)phenyl-l6-sulfanylidene]-2-(trimethylsilyl)ethanesulfonamide (1394013-32-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / dichloromethane / 1 h / 0 °C / Inert atmosphere

1.2: 0 - 20 °C

2.1: N-chloro-succinimide / acetonitrile / 2 h / 20 °C / Inert atmosphere

3.1: acetonitrile / 20 °C

With N-chloro-succinimide; sodium hydride; In dichloromethane; acetonitrile;

DOI:10.1016/j.tet.2012.06.072

Reference yield: 85.0%

N-[morpholin-4-yl(oxido)phenyl-l6-sulfanylidene]-2-(trimethylsilyl)ethanesulfonamide (1394013-32-1) → 4-(S-phenylsulfonimidoyl)morpholine (1394013-36-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 40 ℃; for 6h;

DOI:10.1016/j.tet.2012.06.072

upstream raw materials:

morpholine

benzenesulphinyl chloride

Downstream raw materials:

4-(N-phenylphenylsulfonimidoyl)morpholine

4-(S-phenylsulfonimidoyl)morpholine