BIS(2-PYRROLIDINOETHYL) ETHER

Base Information

• Chemical Name: BIS(2-PYRROLIDINOETHYL) ETHER
• CAS No.: 100396-39-2
• Molecular Formula: C₁₂H₂₄N₂O
• Molecular Weight: 212.335
• Hs Code.: 2933990090
• Mol file: 100396-39-2.mol

Synonyms:Pyrrolidine,1,1'-(oxydiethylene)di- (6CI); Bis(N-pyrrolidinylethyl) ether

Chemical Property of BIS(2-PYRROLIDINOETHYL) ETHER

Chemical Property:

• Vapor Pressure: 0.00339mmHg at 25°C
• Refractive Index: 1.498
• Boiling Point: 282.3°Cat760mmHg
• PKA: 10.05±0.20(Predicted)
• Flash Point: 77.8°C
• PSA: 15.71000
• Density: 0.999g/cm³
• LogP: 1.07040

Purity/Quality:

98%min ^*data from raw suppliers

BIS(2-PYRROLIDINOETHYL)ETHER 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BIS(2-PYRROLIDINOETHYL) ETHER

There total 5 articles about BIS(2-PYRROLIDINOETHYL) ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

N-(2-chloroethyl)-pyrrolidine (5050-41-9) + 1-pyrrolidineethanol (2955-88-6) → bis(2-pyrrolidinoethyl)ether (100396-39-2)

Guidance literature:

With sodium hydroxide; adogen 464; In tetrahydrofuran; for 6h; Heating;

DOI:10.1016/S0022-1139(00)80506-0

Reference yield:

1-(2-(2-(pyrrolidin-1-yl)ethoxy)ethyl)pyrrolidin-2-one → bis(2-pyrrolidinoethyl)ether (100396-39-2)

Guidance literature:

With hydrogen; at 170 ℃; for 48h; under 135014 Torr; Autoclave;

Reference yield:

1-{2-[2-(2-oxo-pyrrolidin-1-yl)-ethoxy]-ethyl}-pyrrolidin-2-one (100526-14-5) → bis(2-pyrrolidinoethyl)ether (100396-39-2) + 1-(2-(2-(pyrrolidin-1-yl)ethoxy)ethyl)pyrrolidin-2-one

Guidance literature:

With hydrogen; at 170 ℃; for 48h; under 135014 Torr; Reagent/catalyst; Temperature; Pressure; Catalytic behavior; Autoclave;

upstream raw materials:

pyrrolidine

3-oxa-1,5-dichloropentane

N-(2-chloroethyl)-pyrrolidine

1-pyrrolidineethanol