Nicotinic acid, 4-amino-5-methyl- (6CI)

Base Information

• Chemical Name: Nicotinic acid, 4-amino-5-methyl- (6CI)
• CAS No.: 100383-06-0
• Molecular Formula: C7H8 N2 O2
• Molecular Weight: 152.153
• Mol file: 100383-06-0.mol

Synonyms:Nicotinicacid, 4-amino-5-methyl- (6CI)

Chemical Property of Nicotinic acid, 4-amino-5-methyl- (6CI)

Chemical Property:

• PSA: 76.94000
• LogP: 0.60050

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-5-methylnicotinicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Nicotinic acid, 4-amino-5-methyl- (6CI)

There total 3 articles about Nicotinic acid, 4-amino-5-methyl- (6CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methyl-4-(4-nitro-phenylazo)-nicotinic acid → 4-amino-5-methyl-nicotinic acid (100383-06-0)

Guidance literature:

With palladium on activated charcoal; sodium carbonate;

DOI:10.1002/ardp.19572901011

Reference yield:

1,7-dimethyl-2-phenyl-1,2-dihydro-pyrazolo[4,3-c]pyridin-3-one (110178-76-2) → 4-amino-5-methyl-nicotinic acid (100383-06-0)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous HNO₃

2: aqueous HNO₃

3: palladium/charcoal; aqueous Na₂CO₃

With palladium on activated charcoal; nitric acid; sodium carbonate;

DOI:10.1002/ardp.19572901011

Reference yield:

1,7-dimethyl-2-(4-nitro-phenyl)-1,2-dihydro-pyrazolo[4,3-c]pyridin-3-one (109127-89-1) → 4-amino-5-methyl-nicotinic acid (100383-06-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous HNO₃

2: palladium/charcoal; aqueous Na₂CO₃

With palladium on activated charcoal; nitric acid; sodium carbonate;

DOI:10.1002/ardp.19572901011

upstream raw materials:

1,7-dimethyl-2-phenyl-1,2-dihydro-pyrazolo[4,3-c]pyridin-3-one

1,7-dimethyl-2-(4-nitro-phenyl)-1,2-dihydro-pyrazolo[4,3-c]pyridin-3-one

Downstream raw materials:

4-amino-3-methylpyridine