benzyl (2R,4R)-4-methoxy-2-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ylcarbamoyl)-pyrrolidine-1-carboxylate trifluoroacetate

Base Information

Chemical Name:benzyl (2R,4R)-4-methoxy-2-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ylcarbamoyl)-pyrrolidine-1-carboxylate trifluoroacetate
CAS No.:957469-32-8
Molecular Formula:C₂HF₃O₂*C₂₄H₂₉N₃O₄
Molecular Weight:537.536
Hs Code.:

Synonyms:benzyl (2R,4R)-4-methoxy-2-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ylcarbamoyl)-pyrrolidine-1-carboxylate trifluoroacetate

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Chemical Property of benzyl (2R,4R)-4-methoxy-2-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ylcarbamoyl)-pyrrolidine-1-carboxylate trifluoroacetate

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Technology Process of benzyl (2R,4R)-4-methoxy-2-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ylcarbamoyl)-pyrrolidine-1-carboxylate trifluoroacetate

There total 1 articles about benzyl (2R,4R)-4-methoxy-2-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ylcarbamoyl)-pyrrolidine-1-carboxylate trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 14097-37-1
2-methyl-1,2,3,4-tetrahydroisoquinolin-6-amine

: 647857-47-4
4R-methoxypyrrolidine-1,2R-dicarboxylic acid 1-benzyl ester 2-methyl ester

: 76-05-1
trifluoroacetic acid

: 957469-32-8
benzyl (2R,4R)-4-methoxy-2-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ylcarbamoyl)-pyrrolidine-1-carboxylate trifluoroacetate

Guidance literature:: 4R-methoxypyrrolidine-1,2R-dicarboxylic acid 1-benzyl ester 2-methyl ester; With trimethylaluminum; In dichloromethane; toluene; for 0.25h;

2-methyl-1,2,3,4-tetrahydroisoquinolin-6-amine; In dichloromethane; toluene; at 20 ℃; for 3h;

trifluoroacetic acid;