2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol

Base Information

Chemical Name:2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol
CAS No.:202459-91-4
Molecular Formula:C₃₄H₄₅NO₆Si
Molecular Weight:591.82
Hs Code.:

Synonyms:2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol

Suppliers and Price of 2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol

There total 6 articles about 2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 202460-05-7
2-azido-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol

: 202459-91-4
2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol

Guidance literature:: With hydrogen; palladium on barium sulfate; In ethanol; ethyl acetate; at 20 ℃; for 30h; under 760 Torr;
DOI:10.1246/bcsj.71.259

Reference yield:

: 202460-00-2
2-azido-2-deoxy-4,5-O-isopropylidene-3-O-(4-methoxybenzyl)-L-mannitol

: 202459-91-4
2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol

Guidance literature:: Multi-step reaction with 9 steps

1: acetic acid / H₂O / 2 h / 50 °C

2: 3.48 g / p-toluenesulfonic acid monohydrate / 5 h / 20 °C

3: 100 percent / imidazole / dimethylformamide / 10.2 h / 0 - 20 °C

4: 100 percent / triethylamine / CH₂Cl₂ / 1.17 h / 0 - 20 °C

5: 75 percent / acetic acid / H₂O / 17 h / 50 °C

6: lead(IV) acetate / benzene / 0.5 h / 20 °C

7: NaBH₄ / methanol / 1 h / 0 - 20 °C

8: 768 mg / sodium methoxide / methanol / 4 h / 0 - 20 °C

9: 75 percent / H₂ / Pd-BaSO₄ / ethyl acetate; ethanol / 30 h / 20 °C / 760 Torr

With 1H-imidazole; lead(IV) acetate; sodium tetrahydroborate; hydrogen; sodium methylate; toluene-4-sulfonic acid; acetic acid; triethylamine; palladium on barium sulfate; In methanol; ethanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; benzene; 1: Hydrolysis / 2: Cyclization / 3: silylation / 4: mesylation / 5: Hydrolysis / 6: Oxidation / 7: Reduction / 8: Cyclization / 9: Hydrogenation;
DOI:10.1246/bcsj.71.259

Reference yield:

: (2S,3S,4S,5S)-5-Azido-4-(4-methoxy-benzyloxy)-hexane-1,2,3,6-tetraol

: 202459-91-4
2-(t-butoxycarbonyl)amino-1-O-(t-butyldiphenylsilyl)-2-deoxy-3-O-(4-methoxybenzyl)-D-4,5-anhydroribitol

Guidance literature:: Multi-step reaction with 8 steps

1: 3.48 g / p-toluenesulfonic acid monohydrate / 5 h / 20 °C

2: 100 percent / imidazole / dimethylformamide / 10.2 h / 0 - 20 °C

3: 100 percent / triethylamine / CH₂Cl₂ / 1.17 h / 0 - 20 °C

4: 75 percent / acetic acid / H₂O / 17 h / 50 °C

5: lead(IV) acetate / benzene / 0.5 h / 20 °C

6: NaBH₄ / methanol / 1 h / 0 - 20 °C

7: 768 mg / sodium methoxide / methanol / 4 h / 0 - 20 °C

8: 75 percent / H₂ / Pd-BaSO₄ / ethyl acetate; ethanol / 30 h / 20 °C / 760 Torr

With 1H-imidazole; lead(IV) acetate; sodium tetrahydroborate; hydrogen; sodium methylate; toluene-4-sulfonic acid; acetic acid; triethylamine; palladium on barium sulfate; In methanol; ethanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; benzene; 1: Cyclization / 2: silylation / 3: mesylation / 4: Hydrolysis / 5: Oxidation / 6: Reduction / 7: Cyclization / 8: Hydrogenation;
DOI:10.1246/bcsj.71.259