1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene

Base Information

Chemical Name:1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene
CAS No.:157890-00-1
Molecular Formula:C₁₉H₁₅BrF₄O
Molecular Weight:415.225
Hs Code.:

Synonyms:1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene

Suppliers and Price of 1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene

There total 3 articles about 1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.6%

: 589-87-7
1,4-bromoiodobenzene

: 156239-78-0
4-<(S)-2'-Methylbutoxy-2,3,5,6-tetrafluorophenyl>acetylene

: 157890-00-1
1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 35 - 40 ℃; for 48h;
DOI:10.1016/0022-1139(94)03048-0

Reference yield:

: 1565-80-6
(2S)-2-methyl-1-butanol

: 157890-00-1
1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene

Guidance literature:: Multi-step reaction with 2 steps

1: 90.3 percent / K₂CO₃ / dimethylformamide / 1.) 35 deg C - 40 deg C, 46 h, 60 deg C - 65 deg C, 6 h

2: 87.6 percent / (Ph₃P)2PdCl₂, CuI, Et₃N / 48 h / 35 - 40 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1016/0022-1139(94)03048-0

Reference yield:

: 52168-00-0
((trimethylsilyl)ethynyl)pentafluorobenzene

: 157890-00-1
1-(4-bromophenyl)-2-<4-((S)-2-methylbutoxy)-2,3,5,6-tetrafluorophenyl>acetylene

Guidance literature:: Multi-step reaction with 2 steps

1: 90.3 percent / K₂CO₃ / dimethylformamide / 1.) 35 deg C - 40 deg C, 46 h, 60 deg C - 65 deg C, 6 h

2: 87.6 percent / (Ph₃P)2PdCl₂, CuI, Et₃N / 48 h / 35 - 40 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1016/0022-1139(94)03048-0