3-(5-amino-3-methyl-1H-pyrazol-4-yl)-3-p-tolylpropanoic acid

Base Information

• Chemical Name: 3-(5-amino-3-methyl-1H-pyrazol-4-yl)-3-p-tolylpropanoic acid
• CAS No.: 1350817-56-9
• Molecular Formula: C₁₄H₁₇N₃O₂
• Molecular Weight: 259.308
• Mol file: 1350817-56-9.mol

Synonyms:3-(5-amino-3-methyl-1H-pyrazol-4-yl)-3-p-tolylpropanoic acid

Chemical Property of 3-(5-amino-3-methyl-1H-pyrazol-4-yl)-3-p-tolylpropanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 3-(5-amino-3-methyl-1H-pyrazol-4-yl)-3-p-tolylpropanoic acid

There total 1 articles about 3-(5-amino-3-methyl-1H-pyrazol-4-yl)-3-p-tolylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

cycl-isopropylidene malonate (2033-24-1) + 4-methyl-benzaldehyde (104-87-0) + 3-methyl-2-pyrazoline-5-one (108-26-9) → 3-(5-amino-3-methyl-1H-pyrazol-4-yl)-3-p-tolylpropanoic acid (1350817-56-9)

Guidance literature:

3-methyl-2-pyrazoline-5-one; With ammonium acetate; at 100 ℃; for 0.166667h; Ionic liquid;

cycl-isopropylidene malonate; 4-methyl-benzaldehyde; at 100 ℃; for 0.5h; Ionic liquid;

With water; at 20 ℃; for 0.0833333h;

DOI:10.1016/j.tetlet.2011.10.099

upstream raw materials:

cycl-isopropylidene malonate

4-methyl-benzaldehyde

3-methyl-2-pyrazoline-5-one