2H-Pyran, 2-(8-dodecynyloxy)tetrahydro-

Base Information

Chemical Name:2H-Pyran, 2-(8-dodecynyloxy)tetrahydro-
CAS No.:64604-68-8
Molecular Formula:C17H30O2
Molecular Weight:266.424
Hs Code.:
DSSTox Substance ID:DTXSID00886689
Nikkaji Number:J1.602.713H

Synonyms:2H-Pyran, 2-(8-dodecynyloxy)tetrahydro-;64604-68-8;2H-Pyran, 2-(8-dodecyn-1-yloxy)tetrahydro-;Tetrahydropyran-2-ol ether of 8-dodecynol;DTXSID00886689;2-(8-Dodecynyloxy)tetrahydro-2H-pyran;8-Dodecynyl tetrahydro-2H-pyran-2-yl ether #

Suppliers and Price of 2H-Pyran, 2-(8-dodecynyloxy)tetrahydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2H-Pyran, 2-(8-dodecynyloxy)tetrahydro-

Chemical Property:

Vapor Pressure:3.19E-05mmHg at 25°C
Refractive Index:1.472
Boiling Point:366 °C at 760 mmHg
Flash Point:125.8 °C
Density:0.93 g/cm³
XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:9
Exact Mass:266.224580195
Heavy Atom Count:19
Complexity:261

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC#CCCCCCCCOC1CCCCO1

Technology Process of 2H-Pyran, 2-(8-dodecynyloxy)tetrahydro-

There total 12 articles about 2H-Pyran, 2-(8-dodecynyloxy)tetrahydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 14752-60-4
pentynyl bromide

: 81744-94-7
7-tetrahydropyranyloxy-heptyl-magnesium chloride

: 64604-68-8
1-(2-tetrahydropyranyloxy)dodec-8-ene

Guidance literature:: In diethyl ether; at 50 ℃; Solvent; Cooling with ice; Inert atmosphere;

Reference yield:

: 20731-23-1
methyl non-8-enoate

: 64604-68-8
1-(2-tetrahydropyranyloxy)dodec-8-ene

Guidance literature:: Multi-step reaction with 5 steps

1: 1) Br₂, 2) aq.KOH / 1) CCl₄, r.t., 2) 135-145 deg C, 4 h

2: 86.2 percent / conc.H₂SO₄ / 4 h / Heating

3: 96 percent / LAH / diethyl ether / 2 h / Ambient temperature

4: 90.6 percent / PPTS / CH₂Cl₂ / 4 h / Ambient temperature

5: 1) n-BuLi, 2) HMPT / 1) THF, hexane, 10 deg C, 2) <25 deg C, 0.5 h

With N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hydroxide; lithium aluminium tetrahydride; n-butyllithium; sulfuric acid; bromine; pyridinium p-toluenesulfonate; In diethyl ether; dichloromethane;

Reference yield:

: 51326-52-4
8-(tetrahydro-2H-pyran-2-yloxy)octan-1-ol

: 64604-68-8
1-(2-tetrahydropyranyloxy)dodec-8-ene

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / pyridinium dichromate / CH₂Cl₂ / 8 h / 25 °C

2: 1.)triphenylphosphine; 2.) zinc / 1.) dichloromethane, 10 min; 2.) 20 deg C, 24 h; 3.) dichloromethane, 25 deg C, 1h;

3: 80 percent / n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

4: n-buthyllithium / 1.) THF and HMPA, hexane, 0 deg C, 30 min; 2.) HMPA, 25 deg C, 20 h;

With dipyridinium dichromate; n-butyllithium; triphenylphosphine; zinc; In tetrahydrofuran; hexane; dichloromethane;