5-((N-Benzyloxycarbonyl)-Piperidin-4-YL)-3-(4-Fluorophenyl)-2-(4-Pyridyl)-Pyrrole

Base Information

Chemical Name:5-((N-Benzyloxycarbonyl)-Piperidin-4-YL)-3-(4-Fluorophenyl)-2-(4-Pyridyl)-Pyrrole
CAS No.:191030-69-0
Molecular Formula:C₂₈H₂₆FN₃O₂
Molecular Weight:455.532
Hs Code.:

Synonyms:5-((N-Benzyloxycarbonyl)-Piperidin-4-YL)-3-(4-Fluorophenyl)-2-(4-Pyridyl)-Pyrrole

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Chemical Property of 5-((N-Benzyloxycarbonyl)-Piperidin-4-YL)-3-(4-Fluorophenyl)-2-(4-Pyridyl)-Pyrrole

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Technology Process of 5-((N-Benzyloxycarbonyl)-Piperidin-4-YL)-3-(4-Fluorophenyl)-2-(4-Pyridyl)-Pyrrole

There total 3 articles about 5-((N-Benzyloxycarbonyl)-Piperidin-4-YL)-3-(4-Fluorophenyl)-2-(4-Pyridyl)-Pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 191038-03-6
4-[3-(4-fluoro-phenyl)-4-oxo-4-pyridin-4-yl-butyryl]-piperidine-1-carboxylic acid benzyl ester

: 191030-69-0
5-((N-Benzyloxycarbonyl)-Piperidin-4-YL)-3-(4-Fluorophenyl)-2-(4-Pyridyl)-Pyrrole

Guidance literature:: With ammonium acetate; acetic acid; at 110 ℃;
DOI:10.1016/S0960-894X(99)00081-5

Reference yield:

: 115858-98-5
1-(4-fluorophenyl)-2-(pyridin-4-yl)-2-ethanone

: 191030-69-0
5-((N-Benzyloxycarbonyl)-Piperidin-4-YL)-3-(4-Fluorophenyl)-2-(4-Pyridyl)-Pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: NaN(TMS)2 / dimethylsulfoxide

2: 90 percent / NH₄OAc, AcOH / 110 °C

With ammonium acetate; sodium hexamethyldisilazane; acetic acid; In dimethyl sulfoxide;
DOI:10.1016/S0960-894X(99)00081-5

Reference yield:

: 816464-47-8
benzyl 4-(2-bromoacetyl)piperidine-1-carboxylate

: 191030-69-0
5-((N-Benzyloxycarbonyl)-Piperidin-4-YL)-3-(4-Fluorophenyl)-2-(4-Pyridyl)-Pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: NaN(TMS)2 / dimethylsulfoxide

2: 90 percent / NH₄OAc, AcOH / 110 °C

With ammonium acetate; sodium hexamethyldisilazane; acetic acid; In dimethyl sulfoxide;
DOI:10.1016/S0960-894X(99)00081-5