C₂₂H₂₂BrN

Base Information

• Chemical Name: C₂₂H₂₂BrN
• CAS No.: 1404115-31-6
• Molecular Formula: C₂₂H₂₂BrN
• Molecular Weight: 380.327
• Mol file: 1404115-31-6.mol

Synonyms:C₂₂H₂₂BrN

Chemical Property of C₂₂H₂₂BrN

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₂BrN

There total 6 articles about C₂₂H₂₂BrN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-2-(2-bromoethyl)benzene (1074-15-3) + dibenzylamine (103-49-1) → C22H22BrN (1404115-31-6)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In toluene; for 21h; Reflux;

DOI:10.1246/cl.180275

Reference yield:

1-Bromo-2-bromomethyl-benzene (3433-80-5) → C22H22BrN (1404115-31-6)

Guidance literature:

Multi-step reaction with 5 steps

1.1: ethanol; water / 4 h / Reflux

2.1: sodium hydroxide; dihydrogen peroxide / ethanol; water / 24 h / Reflux

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C

3.2: 0.5 h / 0 - 20 °C

4.1: phosphorus tribromide / 0 - 100 °C

5.1: N-ethyl-N,N-diisopropylamine / toluene / 21 h / Reflux

With lithium aluminium tetrahydride; dihydrogen peroxide; phosphorus tribromide; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; ethanol; water; toluene;

DOI:10.1246/cl.180275

Reference yield:

2-(2-bromophenyl)acetonitrile (19472-74-3) → C22H22BrN (1404115-31-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydroxide; dihydrogen peroxide / ethanol; water / 24 h / Reflux

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C

2.2: 0.5 h / 0 - 20 °C

3.1: phosphorus tribromide / 0 - 100 °C

4.1: N-ethyl-N,N-diisopropylamine / toluene / 21 h / Reflux

With lithium aluminium tetrahydride; dihydrogen peroxide; phosphorus tribromide; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; ethanol; water; toluene;

DOI:10.1246/cl.180275

upstream raw materials:

2-(2-bromophenyl)ethanamine

benzyl bromide

1-Bromo-2-bromomethyl-benzene

2-(2-bromophenyl)acetonitrile