5-Nitrofuro[2,3-b]pyridine

Base Information

Chemical Name:5-Nitrofuro[2,3-b]pyridine
CAS No.:34668-29-6
Molecular Formula:C₇H₄N₂O₃
Molecular Weight:164.12
Hs Code.:
DSSTox Substance ID:DTXSID301311821

Synonyms:5-nitrofuro[2,3-b]pyridine;34668-29-6;Furo[2,3-b]pyridine, 5-nitro-;DTXSID301311821;SB13382;F84225

Suppliers and Price of 5-Nitrofuro[2,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
5-nitro-Furo[2,3-b]pyridine 97.00%
25G
$ 13300.00

AccelPharmtech
5-nitro-Furo[2,3-b]pyridine 97.00%
5G
$ 5360.00

AccelPharmtech
5-nitro-Furo[2,3-b]pyridine 97.00%
1G
$ 3120.00

Total 6 raw suppliers

Chemical Property of 5-Nitrofuro[2,3-b]pyridine

Chemical Property:

Boiling Point:270.7±20.0 °C(Predicted)
Density:1.473±0.06 g/cm3(Predicted)
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:164.02219199
Heavy Atom Count:12
Complexity:192

Purity/Quality:

97% ^*data from raw suppliers

5-nitro-Furo[2,3-b]pyridine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=COC2=NC=C(C=C21)[N+](=O)[O-]

Technology Process of 5-Nitrofuro[2,3-b]pyridine

There total 1 articles about 5-Nitrofuro[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6563-65-1
5-nitro-furo[2,3-b]pyridine-2-carboxylic acid

: 34668-29-6
5-nitrofuro<2,3-b>pyridine

Guidance literature:: With quinoline; copper; at 185 - 200 ℃; for 3h;

Reference yield:

: 34668-29-6
5-nitrofuro<2,3-b>pyridine

: 220957-39-1
5-bromofuro<2,3-b>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: Al(Hg), water / diethyl ether / 3 h / Ambient temperature

2: 1.) 47 percent aq. HBr, NaNO₂, 2.) CuBr, 37 percent aq. HBr / 1.) 0 deg C, 15 min

With aluminum amalgam; water; hydrogen bromide; copper(I) bromide; sodium nitrite; In diethyl ether;
DOI:10.1002/jhet.5570350611

Reference yield:

: 34668-29-6
5-nitrofuro<2,3-b>pyridine

: 201470-89-5
5-formylfuro<2,3-b>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: Al(Hg), water / diethyl ether / 3 h / Ambient temperature

2: 1.) 35 percent aq. HCl, NaNO₂, 2.) aq. NaCN / 1.) from 0 deg C to 5 deg C, 15 min, 2.) benzene, RT, 3 h

3: 33 percent / DIBAL-H / CH₂Cl₂ / 0.25 h / -50 °C

With hydrogenchloride; aluminum amalgam; sodium cyanide; water; diisobutylaluminium hydride; sodium nitrite; In diethyl ether; dichloromethane;
DOI:10.1002/jhet.5570350611