4-Ethyl-1H-imidazol-2-amine

Base Information

• Chemical Name: 4-Ethyl-1H-imidazol-2-amine
• CAS No.: 19552-53-5
• Molecular Formula: C₅H₉N₃
• Molecular Weight: 111.147
• Hs Code.: 2933290090
• European Community (EC) Number: 819-183-0
• DSSTox Substance ID: DTXSID70473666
• Nikkaji Number: J633.358C
• Wikidata: Q82303239
• Mol file: 19552-53-5.mol

Synonyms:4-Ethyl-1H-imidazol-2-amine;19552-53-5;5-ETHYL-1H-IMIDAZOL-2-AMINE;4-ETHYL-1H-IMIDAZOL-2-YLAMINE;1H-Imidazol-2-amine,4-ethyl-(9CI);5-ethyl-2-aminoimidazole;SCHEMBL3445980;DTXSID70473666;AKOS006347602;AB54794;AT30988;CS-0449285;EN300-123004

Chemical Property of 4-Ethyl-1H-imidazol-2-amine

Chemical Property:

• Boiling Point: 302.3±35.0 °C(Predicted)
• PKA: 15.89±0.10(Predicted)
• PSA: 55.43000
• Density: 1.156±0.06 g/cm3(Predicted)
• LogP: 0.48440
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 111.079647300
• Heavy Atom Count: 8
• Complexity: 74.1

Purity/Quality:

98%min ^*data from raw suppliers

4-Ethyl-1H-imidazol-2-ylamine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=CN=C(N1)N

Technology Process of 4-Ethyl-1H-imidazol-2-amine

There total 3 articles about 4-Ethyl-1H-imidazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

N-<4(5)-Ethyl-1H-imidazol-2-yl>acetamide → 2-Amino-4(5)-ethylimidazole (19552-53-5)

Guidance literature:

With sulfuric acid; In methanol; water; for 24h; Heating;

DOI:10.1021/jo00103a021

Reference yield:

→ 2-Amino-4(5)-ethylimidazole (19552-53-5)

Guidance literature:

With phosphorus; hydrogen iodide;

DOI:10.1246/bcsj.27.539

Reference yield:

→ 2-Amino-4(5)-ethylimidazole (19552-53-5)

Guidance literature:

Downstream raw materials:

C₂₁H₂₃F₃N₄O₂

C₁₇H₁₅ClF₃N₃O

Refernces

• 1、 Little, Thomas L.,Webber, Stephen E.. "A Simple and Practical Synthesis of 2-Aminoimidazoles". . p. 7299 - 7305. Retrieved 2007/10/02.