methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone

Base Information

Chemical Name:methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone
CAS No.:1415974-10-5
Molecular Formula:C₄₃H₄₉N₃O₁₀Si
Molecular Weight:795.962
Hs Code.:

Synonyms:methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone

Suppliers and Price of methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone

There total 6 articles about methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1415973-65-7
methyl 4-O-[2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-3-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone

: 1415974-10-5
methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; water; at 20 ℃; for 4h; chemoselective reaction;
DOI:10.1021/ja3090065

Reference yield:

: 1415974-54-7
6-O-acetyl-4-O-[2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-3-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-2-O-benzoyl-3-O-benzyl-L-idopyranosyl acetate

: 1415974-10-5
methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone

Guidance literature:: Multi-step reaction with 6 steps

1: ammonia / methanol; tetrahydrofuran / 3.05 h / 0 °C

2: potassium carbonate / dichloromethane / 16 h / 20 °C / Inert atmosphere

3: silver trifluoromethanesulfonate / dichloromethane / 1 h / -5 °C / Inert atmosphere; Molecular sieve

4: sodium methylate / methanol; dichloromethane / 20 °C / Inert atmosphere

5: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane; water / 6 h / 20 °C

6: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 4 h / 20 °C

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; ammonia; sodium methylate; silver trifluoromethanesulfonate; potassium carbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1021/ja3090065

Reference yield:

: 6-O-acetyl-4-O-[2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-3-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-2-O-benzoyl-3-O-benzyl-L-idopyranose

: 1415974-10-5
methyl 4-O-(2-azido-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-α-L-idopyranosidurono-6,2-lactone

Guidance literature:: Multi-step reaction with 5 steps

1: potassium carbonate / dichloromethane / 16 h / 20 °C / Inert atmosphere

2: silver trifluoromethanesulfonate / dichloromethane / 1 h / -5 °C / Inert atmosphere; Molecular sieve

3: sodium methylate / methanol; dichloromethane / 20 °C / Inert atmosphere

4: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane; water / 6 h / 20 °C

5: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 4 h / 20 °C

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; sodium methylate; silver trifluoromethanesulfonate; potassium carbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; dichloromethane; water;
DOI:10.1021/ja3090065