a:b-Diaminopropionic Acid Hydrochloride

Base Information

• Chemical Name: a:b-Diaminopropionic Acid Hydrochloride
• CAS No.: 19391-83-4
• Molecular Formula: C4H10 N2 O2 . Cl H
• Molecular Weight: 0
• Mol file: 19391-83-4.mol

Synonyms:Butanoicacid, 2,4-diamino-, monohydrochloride (9CI); Butanoic acid, 2,4-diamino-,monohydrochloride, (?à)-; Butyric acid, 2,4-diamino-, monohydrochloride, DL- (8CI);2,4-Diaminobutanoic acid monohydrochloride

Chemical Property of a:b-Diaminopropionic Acid Hydrochloride

Chemical Property:

• PSA: 89.34000
• LogP: 0.94970

Purity/Quality:

99% ^*data from raw suppliers

DL-2,4-DIAMINOBUTANOIC ACID HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of a:b-Diaminopropionic Acid Hydrochloride

There total 4 articles about a:b-Diaminopropionic Acid Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

Nα,Nγ-bis(t-butoxycarbonyl)-L-α,γ-butyric acid (34404-27-8,752986-92-8) → (S)-2,4-diaminobutyric acid dihydrochloride (1482-98-0,1883-09-6,6970-28-1,19391-83-4,26889-08-7,40149-78-8,57538-26-8,65427-54-5,66837-03-4,89700-93-6,101854-78-8,127531-11-7)

Guidance literature:

With hydrogenchloride;

DOI:10.1016/j.tetlet.2006.11.033

Reference yield:

(S)-3-Cyano-2-[(1R,2R,5R)-2-hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-(3E)-ylideneamino]-propionic acid ethyl ester (127531-09-3,127531-10-6) → (S)-2,4-diaminobutyric acid dihydrochloride (1482-98-0,1883-09-6,6970-28-1,19391-83-4,26889-08-7,40149-78-8,57538-26-8,65427-54-5,66837-03-4,89700-93-6,101854-78-8,127531-11-7)

Guidance literature:

With hydrogenchloride; at 70 ℃; for 5h;

DOI:10.1016/S0040-4039(01)93841-9

Reference yield:

(R)-2,4-Diamino-butyric acid ethyl ester; hydrochloride (103668-08-2) → (R)-2,4-diaminobutyric acid dihydrochloride (1482-98-0,1883-09-6,6970-28-1,19391-83-4,26889-08-7,40149-78-8,57538-26-8,65427-54-5,66837-03-4,89700-93-6,101854-78-8,127531-11-7)

Guidance literature:

With hydrogenchloride; at 70 ℃; for 5h;

DOI:10.1016/S0040-4039(01)93841-9

upstream raw materials:

(S)-3-Cyano-2-[(1R,2R,5R)-2-hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-(3E)-ylideneamino]-propionic acid ethyl ester

N^α,N^γ-bis(t-butoxycarbonyl)-L-α,γ-butyric acid

(R)-2,4-Diamino-butyric acid ethyl ester; hydrochloride

Downstream raw materials:

N^α,N^γ-diBoc-L-2,4-diaminobutyric acid p-nitrobenzyl ester

DPAB-L-DBA (trans)

(R)-2,4-bis((((9H-fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid

(S)-2,4-bis(((benzyloxy)carbonyl)amino)butanoic acid

Refernces

• 1、 Solladie-Cavallo, A.,Simon, M. C.. "ENANTIOSELECTIVE SYNTHESIS OF OPTICALLY PURE NATURAL S(+) OR UNNATURAL R(-) DABA". . p. 6011 - 6014. Retrieved 2007/10/02.