clavulanic acid p-nitrobenzyl ester

Base Information

Chemical Name:clavulanic acid p-nitrobenzyl ester
CAS No.:57943-83-6
Molecular Formula:C₁₅H₁₄N₂O₇
Molecular Weight:334.285
Hs Code.:

Synonyms:clavulanic acid p-nitrobenzyl ester

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Chemical Property of clavulanic acid p-nitrobenzyl ester

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Technology Process of clavulanic acid p-nitrobenzyl ester

There total 7 articles about clavulanic acid p-nitrobenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 57943-81-4
potassium clavulanate

: 57943-83-6
clavulanic acid p-nitrobenzyl ester

Guidance literature:: In N,N-dimethyl-formamide; for 1.5h; Ambient temperature;

Reference yield:

: 57943-82-5
methyl clavulanate

: 57943-83-6
clavulanic acid p-nitrobenzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / sodium hydroxide / H₂O / 1.17 h / 0 °C

2: 60 percent / dimethylformamide / 1.5 h / Ambient temperature

With sodium hydroxide; In water; N,N-dimethyl-formamide;

Reference yield:

: 57943-84-7
Benzyl Clavulanate

: 57943-83-6
clavulanic acid p-nitrobenzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / H₂, sodium hydrogen carbonate / palladium on carbon / aq. ethanol / 0.42 h / Ambient temperature

2: 60 percent / dimethylformamide / 1.5 h / Ambient temperature

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;