ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate

Base Information

Chemical Name:ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate
CAS No.:1010412-84-6
Molecular Formula:C₃₉H₄₁NO₄
Molecular Weight:587.759
Hs Code.:

Synonyms:ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate

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Chemical Property of ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate

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Technology Process of ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate

There total 1 articles about ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1018719-39-5
C₂₉H₂₈BrNO₄

: 123324-71-0
p-tert-butylphenylboronic acid

: 1010412-84-6
ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate

Guidance literature:: With sodium hydrogencarbonate; palladium 10% on activated carbon; In water; N,N-dimethyl-formamide; at 100 ℃; for 24h;

Reference yield: 97.0%

: 1010412-84-6
ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate

: 1010412-85-7
ethyl 3-(4-tert-butylphenyl)-1-[3-(cyclopropylmethoxy)-5-hydroxybenzyl]-1H-indole-2-carboxylate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; chloroform; for 1h; under 760.051 Torr;

Reference yield: 39.0%

: 1010412-84-6
ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate

: 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylic acid

Guidance literature:: ethyl 1-[3-(benzyloxy)-5-(cyclopropylmethoxy)benzyl]-3-(4-tert-butylphenyl)-1H-indole-2-carboxylate; With methanol; sodium hydroxide; water; In tetrahydrofuran; at 50 ℃; for 12h;

With hydrogenchloride; water; In tetrahydrofuran;