2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester

Base Information

Chemical Name:2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester
CAS No.:357172-76-0
Molecular Formula:C₂₅H₃₄O₃Si
Molecular Weight:410.629
Hs Code.:

Synonyms:2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester

Suppliers and Price of 2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester

There total 6 articles about 2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 871-84-1
1,7-Octadiyne

: 2-bromo-3-[2-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-acrylic acid methyl ester

: 357172-76-0
2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester

Guidance literature:: With triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 15h;
DOI:10.1016/S0040-4039(01)00708-0

Reference yield:

: 52753-91-0,132316-45-1
(E)-methyl 3-(2-formylphenyl)acrylate

: 357172-76-0
2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: NaBH₄ / aq. methanol / 2 h / 0 °C

2: 96 percent / imidazole / dimethylformamide / 0.25 h / 20 °C

3: Br₂ / CH₂Cl₂ / 0 °C

4: Et₃N / CH₂Cl₂ / 2 h / 20 °C

5: 40 percent / Et₃N / Pd(PPh₃)4; CuI / tetrahydrofuran / 15 h / 20 °C

With 1H-imidazole; sodium tetrahydroborate; bromine; triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)00708-0

Reference yield:

: 216572-78-0
3-(2-hydroxymethylphenyl)acrylic acid methyl ester

: 357172-76-0
2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-deca-3,9-diynoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 96 percent / imidazole / dimethylformamide / 0.25 h / 20 °C

2: Br₂ / CH₂Cl₂ / 0 °C

3: Et₃N / CH₂Cl₂ / 2 h / 20 °C

4: 40 percent / Et₃N / Pd(PPh₃)4; CuI / tetrahydrofuran / 15 h / 20 °C

With 1H-imidazole; bromine; triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)00708-0