4-(2-hexyl-2H-tetrazol-5-yl)phenyl 4-hexyloxybenzoate

Base Information

• Chemical Name: 4-(2-hexyl-2H-tetrazol-5-yl)phenyl 4-hexyloxybenzoate
• CAS No.: 1451058-55-1
• Molecular Formula: C₂₆H₃₄N₄O₃
• Molecular Weight: 450.581
• Mol file: 1451058-55-1.mol

Synonyms:4-(2-hexyl-2H-tetrazol-5-yl)phenyl 4-hexyloxybenzoate

Chemical Property of 4-(2-hexyl-2H-tetrazol-5-yl)phenyl 4-hexyloxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2-hexyl-2H-tetrazol-5-yl)phenyl 4-hexyloxybenzoate

There total 4 articles about 4-(2-hexyl-2H-tetrazol-5-yl)phenyl 4-hexyloxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

para-hexyloxybenzoic acid (1142-39-8) + 4-(2-hexyl-2H-tetrazol-5-yl)phenol (1176334-35-2) → 4-(2-hexyl-2H-tetrazol-5-yl)phenyl 4-hexyloxybenzoate (1451058-55-1)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1039/c3tc30966e

Reference yield:

4-cyanophenol (767-00-0) → 4-(2-hexyl-2H-tetrazol-5-yl)phenyl 4-hexyloxybenzoate (1451058-55-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium azide; ammonium chloride / N,N-dimethyl-formamide / 24 h / 120 °C

2.1: sodium hydroxide / water / 0.5 h / Cooling with ice

3.1: potassium carbonate / acetone / 48 h / Reflux

4.1: potassium hydroxide / water; methanol / 12 h / Reflux

4.2: pH 2 / Cooling with ice

5.1: dicyclohexyl-carbodiimide; dmap / tetrahydrofuran / 24 h / 20 °C

With dmap; sodium azide; potassium carbonate; ammonium chloride; dicyclohexyl-carbodiimide; potassium hydroxide; sodium hydroxide; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; acetone;

DOI:10.1039/c3tc30966e

Reference yield:

5-(4-hydroxyphenyl)tetrazole (51517-88-5) → 4-(2-hexyl-2H-tetrazol-5-yl)phenyl 4-hexyloxybenzoate (1451058-55-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydroxide / water / 0.5 h / Cooling with ice

2.1: potassium carbonate / acetone / 48 h / Reflux

3.1: potassium hydroxide / water; methanol / 12 h / Reflux

3.2: pH 2 / Cooling with ice

4.1: dicyclohexyl-carbodiimide; dmap / tetrahydrofuran / 24 h / 20 °C

With dmap; potassium carbonate; dicyclohexyl-carbodiimide; potassium hydroxide; sodium hydroxide; In tetrahydrofuran; methanol; water; acetone;

DOI:10.1039/c3tc30966e

upstream raw materials:

4-cyanophenol

para-hexyloxybenzoic acid

4-(2-hexyl-2H-tetrazol-5-yl)phenol

5-(4-hydroxyphenyl)tetrazole