Acetic acid (1R,2R,3S,4R,5R,6S)-4-benzyloxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dihydroxy-cyclohexyl ester

Base Information

• Chemical Name: Acetic acid (1R,2R,3S,4R,5R,6S)-4-benzyloxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dihydroxy-cyclohexyl ester
• CAS No.: 139209-39-5
• Molecular Formula: C₂₇H₄₈O₇Si₂
• Molecular Weight: 540.845
• Mol file: 139209-39-5.mol

Synonyms:Acetic acid (1R,2R,3S,4R,5R,6S)-4-benzyloxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dihydroxy-cyclohexyl ester

Chemical Property of Acetic acid (1R,2R,3S,4R,5R,6S)-4-benzyloxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dihydroxy-cyclohexyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid (1R,2R,3S,4R,5R,6S)-4-benzyloxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dihydroxy-cyclohexyl ester

There total 2 articles about Acetic acid (1R,2R,3S,4R,5R,6S)-4-benzyloxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dihydroxy-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Acetic acid (1S,4S,5R,6R)-5-benzyloxy-4,6-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohex-2-enyl ester → Acetic acid (1R,2R,3S,4R,5R,6S)-4-benzyloxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dihydroxy-cyclohexyl ester (139209-39-5) + Acetic acid (1S,2S,3R,4S,5S,6R)-3-benzyloxy-2,4-bis-(tert-butyl-dimethyl-silanyloxy)-5,6-dihydroxy-cyclohexyl ester + 1-O-acetyl-5-O-benzyl-4,6-bis-O-(tert-butyldimethylsilyl)-DL-myo-inositol

Guidance literature:

With osmium(VIII) oxide; trimethylamine-N-oxide; In water; acetone; tert-butyl alcohol; Yield given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jo00120a046

Reference yield:

Acetic acid (1S,4S,5R,6R)-5-benzyloxy-4,6-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohex-2-enyl ester (139209-36-2) → Acetic acid (1R,2R,3S,4R,5R,6S)-4-benzyloxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dihydroxy-cyclohexyl ester (139209-39-5) + Acetic acid (1S,2S,3R,4S,5R,6S)-3-benzyloxy-2,4-bis-(tert-butyl-dimethyl-silanyloxy)-5,6-dihydroxy-cyclohexyl ester (139209-37-3)

Guidance literature:

With osmium(VIII) oxide; triethylamine N-oxide; In water; acetone; for 24h; Yield given. Yields of byproduct given; Ambient temperature;

DOI:10.1016/0040-4039(91)80506-2

upstream raw materials:

Acetic acid (1S,4S,5R,6R)-5-benzyloxy-4,6-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohex-2-enyl ester