Technology Process of N-(2-((4-methyl-6-((3,4,5-trimethoxyphenyl)amino)-1,3,5-triazin-2-yl)amino)phenyl)acetamide
There total 5 articles about N-(2-((4-methyl-6-((3,4,5-trimethoxyphenyl)amino)-1,3,5-triazin-2-yl)amino)phenyl)acetamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium methylate / tetrahydrofuran / 0.33 h / 70 °C / Microwave irradiation
2: 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; palladium diacetate; caesium carbonate / 1,4-dioxane / 150 °C / Microwave irradiation
3: 2-amino-N-ethylbenzamide; palladium 10% on activated carbon / methanol / Inert atmosphere
4: pyridine / 5 h / 50 °C
With
pyridine; palladium 10% on activated carbon; 2-amino-N-ethylbenzamide; sodium methylate; palladium diacetate; caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene;
In
tetrahydrofuran; 1,4-dioxane; methanol;
DOI:10.1016/j.bmcl.2013.06.038
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2-amino-N-ethylbenzamide; palladium 10% on activated carbon / methanol / Inert atmosphere
2: pyridine / 5 h / 50 °C
With
pyridine; palladium 10% on activated carbon; 2-amino-N-ethylbenzamide;
In
methanol;
DOI:10.1016/j.bmcl.2013.06.038
