5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one

Base Information

• Chemical Name: 5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one
• CAS No.: 71885-64-8
• Molecular Formula: C₂₂H₂₀N₂O₃
• Molecular Weight: 360.412

Synonyms:5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one

Chemical Property of 5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one

There total 11 articles about 5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

spiro<12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole-9,2':5',5'-dimethyl-1',3'-dioxane> (80627-96-9) → 5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one (71885-64-8)

Guidance literature:

With hydrogenchloride; acetic acid; at 80 ℃; for 1.5h;

DOI:10.1021/jo00345a004

Reference yield: 92.0%

5-methyl-9α-hydroxy-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole (80628-05-3) → 5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one (71885-64-8)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; 1.) -78 deg C, 30 min, 2.) from -78 deg C to room temperature;

DOI:10.1021/jo00345a004

Reference yield:

N-methyl-2,6-diacetoxy-9-azabicyclo<3.3.1>nonane (57639-00-6) → 5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one (71885-64-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 71 percent / LiI / acetone / 1.) 0 deg C, 2.) 25 deg C, 3.5 h

2: 98 percent / K₂CO₃ / methanol; H₂O / 2 h / Ambient temperature

3: 94 percent / poly(vinylpyridinium chlorochromate) (PVPCC) / CH₂Cl₂ / 168 h / Ambient temperature

4: 82 percent / dimethylformamide / 0.75 h / 100 °C

5: 92 percent / 1.) dimethyl sulfoxide, oxalyl chloride, 2.) triethylamine / CH₂Cl₂ / 1.) -78 deg C, 30 min, 2.) from -78 deg C to room temperature

With oxalyl dichloride; poly(vinylpyridinium chlorochromate); potassium carbonate; dimethyl sulfoxide; triethylamine; lithium iodide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; acetone;

DOI:10.1021/jo00345a004

upstream raw materials:

5-methyl-9α-hydroxy-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

spiro<12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole-9,2':5',5'-dimethyl-1',3'-dioxane>

N-methyl-2,6-diacetoxy-9-azabicyclo<3.3.1>nonane

phenylhydrazine hydrochloride

Downstream raw materials:

C₂₆H₂₈N₂O₅

5-methyl-9,9-dimethoxy-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

C₂₆H₂₈N₂O₄S₂

spiro<5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole-9,2':1',3'-dioxep-5'-ene>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 71885-64-8 5-methyl-12-(carbophenoxy)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindol-9-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send