C₂₁H₂₁FN₆O₄

Base Information

Chemical Name:C₂₁H₂₁FN₆O₄
CAS No.:1401341-59-0
Molecular Formula:C₂₁H₂₁FN₆O₄
Molecular Weight:440.434
Hs Code.:

C<sub>21</sub>H<sub>21</sub>FN<sub>6</sub>O<sub>4</sub>

Synonyms:C₂₁H₂₁FN₆O₄

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₁H₂₁FN₆O₄

Chemical Property:

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Technology Process of C₂₁H₂₁FN₆O₄

There total 9 articles about C₂₁H₂₁FN₆O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 504437-66-5
(S)‐N‐((3‐(3‐fluoro‐4‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)phenyl)‐2‐oxooxazolidin‐5‐yl)methyl)acetamide

: 1401342-70-8
C₉H₉BrN₄O

: 1401341-59-0
C₂₁H₂₁FN₆O₄

Guidance literature:: With sodium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 2h;

Reference yield:

: 1401342-69-5
C₇H₁₁BrN₄

: 1401341-59-0
C₂₁H₂₁FN₆O₄

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; sodium acetate / 4 h / Reflux

2: sodium carbonate / N,N-dimethyl-formamide / 2 h / 90 °C

With sodium acetate; sodium carbonate; acetic acid; In N,N-dimethyl-formamide;

Reference yield:

: 510729-01-8
(4-bromo-3-fluorophenyl)carbamic acid benzyl ester

: 1401341-59-0
C₂₁H₂₁FN₆O₄

Guidance literature:: Multi-step reaction with 6 steps

1.1: lithium tert-butoxide / N,N-dimethyl-formamide; methanol; tetrahydrofuran / 3 h / 0 - 20 °C

2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1.33 h / 0 - 20 °C

3.1: sodium azide / N,N-dimethyl-formamide / 3 h / 90 °C

4.1: iron; ammonium chloride / water; ethanol / 12 h / Reflux

4.2: 1 h / 20 °C

5.1: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 15 h / 90 °C / Inert atmosphere

6.1: sodium carbonate / N,N-dimethyl-formamide / 2 h / 90 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium azide; potassium acetate; iron; sodium carbonate; ammonium chloride; N-ethyl-N,N-diisopropylamine; lithium tert-butoxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;