Technology Process of (3R*,4R*)-4-(1,1-dimethylethyl)-3-hydroxycyclohexanone
There total 5 articles about (3R*,4R*)-4-(1,1-dimethylethyl)-3-hydroxycyclohexanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
acetic acid;
In
tetrahydrofuran;
for 6h;
Ambient temperature;
DOI:10.1021/ja00219a035
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 82 percent / p-toluenesulfonic acid / 8 h / Ambient temperature
2: borane methyl sulfide / diethyl ether / 8 h / Ambient temperature
3: 81 percent / pyridinium dichromate, pyridinium trifluoroacetate / CH2Cl2 / 14 h / Ambient temperature
4: L-Selectride / tetrahydrofuran / 4 h
5: 36 percent / 50percent aq. acetic acid / tetrahydrofuran / 6 h / Ambient temperature
With
dipyridinium dichromate; dimethylsulfide borane complex; pyridinium trifluroacetate; L-Selectride; acetic acid;
toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/ja00219a035
- Guidance literature:
-
Multi-step reaction with 4 steps
1: borane methyl sulfide / diethyl ether / 8 h / Ambient temperature
2: 81 percent / pyridinium dichromate, pyridinium trifluoroacetate / CH2Cl2 / 14 h / Ambient temperature
3: L-Selectride / tetrahydrofuran / 4 h
4: 36 percent / 50percent aq. acetic acid / tetrahydrofuran / 6 h / Ambient temperature
With
dipyridinium dichromate; dimethylsulfide borane complex; pyridinium trifluroacetate; L-Selectride; acetic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/ja00219a035
