Technology Process of 3,5-dimethyl-8-phenyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
There total 5 articles about 3,5-dimethyl-8-phenyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); phosphate potassium salt;
In
1,4-dioxane;
at 60 ℃;
for 0.75h;
DOI:10.1021/ol3028225
- Guidance literature:
-
With
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; copper(I) thiophene-2-carboxylate; trifuran-2-yl-phosphane;
In
tetrahydrofuran;
at 55 ℃;
for 1.25h;
Inert atmosphere;
Schlenk technique;
DOI:10.1002/ejoc.201600724
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: trichlorophosphate / 1,2-dichloro-ethane / 3 h / Reflux
1.2: 0.08 h / 0 °C
1.3: 2 h / 0 - 20 °C
2.1: tetrakis(triphenylphosphine) palladium(0); phosphate potassium salt / 1,4-dioxane / 0.75 h / 60 °C
With
tetrakis(triphenylphosphine) palladium(0); phosphate potassium salt; trichlorophosphate;
In
1,4-dioxane; 1,2-dichloro-ethane;
2.1: |Suzuki Coupling;
DOI:10.1021/ol3028225
