Technology Process of 1-(2,5-dimethoxyphenyl)-2-(3-fluoro-5-methoxyphenyl)ethanone
There total 6 articles about 1-(2,5-dimethoxyphenyl)-2-(3-fluoro-5-methoxyphenyl)ethanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
polyphosphoric acid;
at 80 ℃;
for 3h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium iodide / water; dimethyl sulfoxide / 6 h / 45 °C
2.1: sodium hydroxide; water / methanol / 4 h / 65 °C
2.2: 20 °C / pH 4 - 5
3.1: polyphosphoric acid / 3 h / 80 °C
With
water; potassium iodide; sodium hydroxide;
In
methanol; water; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: phosphorus pentachloride / tetrachloromethane / 1 h / 20 °C
2.1: potassium iodide / water; dimethyl sulfoxide / 6 h / 45 °C
3.1: sodium hydroxide; water / methanol / 4 h / 65 °C
3.2: 20 °C / pH 4 - 5
4.1: polyphosphoric acid / 3 h / 80 °C
With
phosphorus pentachloride; water; potassium iodide; sodium hydroxide;
In
methanol; tetrachloromethane; water; dimethyl sulfoxide;
