ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate

Base Information

Chemical Name:ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate
CAS No.:1186429-39-9
Molecular Formula:C₂₂H₂₄F₃NO₂Si
Molecular Weight:419.519
Hs Code.:

Synonyms:ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate

Suppliers and Price of ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate

Chemical Property:

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Technology Process of ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate

There total 2 articles about ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 349-75-7
3-(trifluoromethyl)benzyl alcohol

: 1173705-86-6
ethyl 6-trimethylsilyl-1H-indole-2-carboxylate

: 1186429-39-9
ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate

Guidance literature:: With cyanomethylenetributyl-phosphorane; In toluene; at 20 - 110 ℃; for 15h; Inert atmosphere;

Reference yield:

: 1186429-39-9
ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate

Guidance literature:

Reference yield:

: 1186429-39-9
ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate

: 1186429-40-2
6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylic acid

Guidance literature:: ethyl 6-trimethylsilyl-1-[[(3-trifluoromethyl)phenyl]methyl]-1H-indole-2-carboxylate; With water; potassium hydroxide; In ethanol; at 85 ℃; for 2h;

With hydrogenchloride; In water; pH=5;