2,5-dimethoxy-4-(2-trimethylsilylethynyl)benzenecarbaldehyde

Base Information

• Chemical Name: 2,5-dimethoxy-4-(2-trimethylsilylethynyl)benzenecarbaldehyde
• CAS No.: 1208264-49-6
• Molecular Formula: C₁₄H₁₈O₃Si
• Molecular Weight: 262.381
• Mol file: 1208264-49-6.mol

Synonyms:2,5-dimethoxy-4-(2-trimethylsilylethynyl)benzenecarbaldehyde

Chemical Property of 2,5-dimethoxy-4-(2-trimethylsilylethynyl)benzenecarbaldehyde

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2,5-dimethoxy-4-(2-trimethylsilylethynyl)benzenecarbaldehyde

There total 1 articles about 2,5-dimethoxy-4-(2-trimethylsilylethynyl)benzenecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.6%

4-iodo-2,5-dimethoxybenzenecarbaldehyde (90064-47-4) + trimethylsilylacetylene (1066-54-2) → 2,5-dimethoxy-4-(2-trimethylsilylethynyl)benzenecarbaldehyde (1208264-49-6)

Guidance literature:

With piperidine; copper(l) iodide; triphenylphosphine; palladium dichloride; at 20 ℃;

DOI:10.1016/j.bmcl.2009.10.120

Reference yield: 100.0%

2,5-dimethoxy-4-(2-trimethylsilylethynyl)benzenecarbaldehyde (1208264-49-6) → 4-ethynyl-2,5-dimethoxybenzenecarbaldehyde (1208264-50-9)

Guidance literature:

With water; sodium hydroxide; In methanol; chloroform; at 20 ℃; for 4h;

DOI:10.1016/j.bmcl.2009.10.120

upstream raw materials:

4-iodo-2,5-dimethoxybenzenecarbaldehyde

trimethylsilylacetylene

Downstream raw materials:

4-ethynyl-2,5-dimethoxybenzenecarbaldehyde