6-acetoxy-5-benzyloxy-3',4'-diphenylmethylenedioxy-7-methoxyflavone

Base Information

• Chemical Name: 6-acetoxy-5-benzyloxy-3',4'-diphenylmethylenedioxy-7-methoxyflavone
• CAS No.: 104480-97-9
• Molecular Formula: C₃₈H₂₈O₈
• Molecular Weight: 612.636
• Mol file: 104480-97-9.mol

Synonyms:6-acetoxy-5-benzyloxy-3',4'-diphenylmethylenedioxy-7-methoxyflavone

Chemical Property of 6-acetoxy-5-benzyloxy-3',4'-diphenylmethylenedioxy-7-methoxyflavone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-acetoxy-5-benzyloxy-3',4'-diphenylmethylenedioxy-7-methoxyflavone

There total 4 articles about 6-acetoxy-5-benzyloxy-3',4'-diphenylmethylenedioxy-7-methoxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

benzyl chloride (100-44-7) + 6-acetoxy-3',4'-diphenylmethylenedioxy-5-hydroxy-7-methoxyflavone (104480-96-8) → 6-acetoxy-5-benzyloxy-3',4'-diphenylmethylenedioxy-7-methoxyflavone (104480-97-9)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 5h; Heating;

DOI:10.1248/cpb.34.30

Reference yield:

5,6,3',4'-tetrahydroxy-7-methoxyflavone (22384-63-0) → 6-acetoxy-5-benzyloxy-3',4'-diphenylmethylenedioxy-7-methoxyflavone (104480-97-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 76 percent / melt / 0.08 h / 230 °C

2: 78 percent / acetic acid; H₂O / 0.17 h / Heating

3: 86 percent / pyridine / 0.03 h / 90 °C

4: 60 percent / potassium iodide, potassium carbonate / acetone / 5 h / Heating

With potassium carbonate; potassium iodide; In pyridine; water; acetic acid; acetone;

DOI:10.1248/cpb.34.30

Reference yield:

3',4'-diphenylmethylenedioxy-5,6-dihydroxy-7-methoxyflavone (104480-95-7) → 6-acetoxy-5-benzyloxy-3',4'-diphenylmethylenedioxy-7-methoxyflavone (104480-97-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / pyridine / 0.03 h / 90 °C

2: 60 percent / potassium iodide, potassium carbonate / acetone / 5 h / Heating

With potassium carbonate; potassium iodide; In pyridine; acetone;

DOI:10.1248/cpb.34.30

upstream raw materials:

benzyl chloride

6-acetoxy-3',4'-diphenylmethylenedioxy-5-hydroxy-7-methoxyflavone

5,6,3',4'-tetrahydroxy-7-methoxyflavone

3',4'-diphenylmethylenedioxy-5,6-dihydroxy-7-methoxyflavone

Downstream raw materials:

5-benzyloxy-3',4'-diphenylmethylenedioxy-6-hydroxy-7-methoxyflavone