2-(3-Phenylpiperidin-1-yl)ethanamine

Base Information

• Chemical Name: 2-(3-Phenylpiperidin-1-yl)ethanamine
• CAS No.: 862718-71-6
• Molecular Formula: C₁₃H₂₀N₂
• Molecular Weight: 204.315
• DSSTox Substance ID: DTXSID90344829
• Mol file: 862718-71-6.mol

Synonyms:2-(3-phenylpiperidin-1-yl)ethanamine;862718-71-6;CHEMBRDG-BB 4004740;2-(3-Phenyl-piperidin-1-yl)-ethylamine;DTXSID90344829;AKOS006342694;2-(3-Phenyl-1-piperidinyl)ethanamine #;2-(3-phenylpiperidin-1-yl)ethan-1-amine

Chemical Property of 2-(3-Phenylpiperidin-1-yl)ethanamine

Chemical Property:

• Vapor Pressure: 0.000262mmHg at 25°C
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 204.162648646
• Heavy Atom Count: 15
• Complexity: 175

Purity/Quality:

2-(3-PHENYLPIPERIDIN-1-YL)ETHANAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC(CN(C1)CCN)C2=CC=CC=C2

Technology Process of 2-(3-Phenylpiperidin-1-yl)ethanamine

There total 1 articles about 2-(3-Phenylpiperidin-1-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2-[2-(3-phenyl-piperidin-1-yl)-ethyl]-isoindole-1,3-dione (877168-42-8) → 2-(3-phenylpiperidin-1-yl)ethylamine (862718-71-6)

Guidance literature:

With hydrazine hydrate; In methanol; at 80 ℃; for 2h;

DOI:10.1016/j.bmc.2005.04.060

Reference yield:

2-(3-phenylpiperidin-1-yl)ethylamine (862718-71-6) + 2-chloro-1,3-benzoxazole (615-18-9) → N-(benzoxazol-2-yl)[2-(3-phenylpiperidin-1-yl)ethyl]amine

Guidance literature:

With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; Heating;

DOI:10.1016/j.bmc.2005.04.060

Reference yield:

2-(3-phenylpiperidin-1-yl)ethylamine (862718-71-6) + 2-chloro-1-methyl-benzimidazole (1849-02-1) → N-(1-methyl-1H-benzimidazol-2-yl)[2-(3-phenylpiperidin-1-yl)ethyl]amine

Guidance literature:

With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; Heating;

DOI:10.1016/j.bmc.2005.04.060

upstream raw materials:

2-[2-(3-phenyl-piperidin-1-yl)-ethyl]-isoindole-1,3-dione