N-[4-(3-bromo-2-oxo-pyrrolidin-1-yl)-phenyl]-4-cyclohexyl-N-methylbenzamide

Base Information

• Chemical Name: N-[4-(3-bromo-2-oxo-pyrrolidin-1-yl)-phenyl]-4-cyclohexyl-N-methylbenzamide
• CAS No.: 748183-75-7
• Molecular Formula: C₂₄H₂₇BrN₂O₂
• Molecular Weight: 455.395

Synonyms:N-[4-(3-bromo-2-oxo-pyrrolidin-1-yl)-phenyl]-4-cyclohexyl-N-methylbenzamide

Chemical Property of N-[4-(3-bromo-2-oxo-pyrrolidin-1-yl)-phenyl]-4-cyclohexyl-N-methylbenzamide

Chemical Property:

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Technology Process of N-[4-(3-bromo-2-oxo-pyrrolidin-1-yl)-phenyl]-4-cyclohexyl-N-methylbenzamide

There total 1 articles about N-[4-(3-bromo-2-oxo-pyrrolidin-1-yl)-phenyl]-4-cyclohexyl-N-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4-Aminophenyl)-4-cyclohexyl-N-methylbenzamide (748183-76-8) + 2-bromo-4-chloro butyryl bromide (1719-99-9) + sodium phosphate → N-[4-(3-bromo-2-oxo-pyrrolidin-1-yl)-phenyl]-4-cyclohexyl-N-methylbenzamide (748183-75-7)

Guidance literature:

With sodium hydroxide; In n-heptane; water; acetonitrile;

Reference yield:

7-aza-bicyclo[2.2.1]heptane (279-40-3) + N-[4-(3-bromo-2-oxo-pyrrolidin-1-yl)-phenyl]-4-cyclohexyl-N-methylbenzamide (748183-75-7) → N-[4-[3-(7-azabicyclo[2.2.1]hept-7-yl)-2-oxo-pyrrolidin-1-yl]-phenyl]-4-cyclohexyl-N-methylbenzamide

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

Reference yield:

piperidine (110-89-4) + N-[4-(3-bromo-2-oxo-pyrrolidin-1-yl)-phenyl]-4-cyclohexyl-N-methylbenzamide (748183-75-7) → 4-Cyclohexyl-N-methyl-N-[4-(2-oxo-3-piperidin-1-ylpyrrolidin-1-yl)phenyl]benzamide (748168-89-0)

Guidance literature:

upstream raw materials:

N-(4-Aminophenyl)-4-cyclohexyl-N-methylbenzamide

2-bromo-4-chloro butyryl bromide

Downstream raw materials:

4-Cyclohexyl-N-methyl-N-[4-(2-oxo-3-piperidin-1-ylpyrrolidin-1-yl)phenyl]benzamide

4-Cyclohexyl-N-methyl-N-[4-(3-morpholin-4-yl-2-oxopyrrolidin-1-yl)phenyl]benzamide

4-Cyclohexyl-N-methyl-N-[4-(2'-oxo[1,3']bipyrrolidinyl-1'-yl)phenyl]benzamide

4-Cyclohexyl-N-[4-(3-cyclohexylamino-2-oxopyrrolidin-1-yl)phenyl]-N-methylbenzamide

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