6-Methyl-1H-indole-2-carboxylic acid

Base Information

Chemical Name:6-Methyl-1H-indole-2-carboxylic acid
CAS No.:18474-59-4
Molecular Formula:C10H9NO2
Molecular Weight:175.187
Hs Code.:2933990090
European Community (EC) Number:692-294-8
DSSTox Substance ID:DTXSID70390349
Wikidata:Q27454576
ChEMBL ID:CHEMBL596007
Mol file:18474-59-4.mol

Synonyms:6-Methyl-1H-indole-2-carboxylic acid;18474-59-4;6-Methylindole-2-carboxylic acid;eIF4A3-IN-8;1H-Indole-2-carboxylicacid, 6-methyl-;CHEMBL596007;MFCD02664477;4BL;SCHEMBL1144688;DTXSID70390349;ZKGSVVHFMZASJS-UHFFFAOYSA-N;HMS1630E02;AMY40742;BBL020943;BDBM50305666;STK893649;AKOS000118128;FS-2410;SB15196;NCGC00337851-01;HY-33838;6-METHYL-1H-INDOLE-2-CARBOXYLICACID;BB 0216437;CS-0018975;FT-0677786;EN300-15104;AB01329949-02;6-Methyl-1H-indole-2-carboxylic acid, AldrichCPR;J-518910;Q27454576;Z119989628

Suppliers and Price of 6-Methyl-1H-indole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Methyl-1H-indole-2-carboxylicAcid
500mg
$ 265.00

Matrix Scientific
6-Methyl-1H-indole-2-carboxylic acid
500mg
$ 90.00

Matrix Scientific
6-Methyl-1H-indole-2-carboxylic acid
1g
$ 147.00

Labseeker
6-METHYLINDOLE-2-CARBOXYLICACID 95
1g
$ 462.00

Chemenu
6-Methyl-1H-indole-2-carboxylicacid 95%+
5g
$ 555.00

American Custom Chemicals Corporation
6-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 95.00%
1G
$ 808.89

American Custom Chemicals Corporation
6-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 95.00%
5G
$ 1421.65

American Custom Chemicals Corporation
6-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 95.00%
2.5G
$ 1147.43

Ambeed
6-Methyl-1H-indole-2-carboxylicacid 98%
1g
$ 126.00

Ambeed
6-Methyl-1H-indole-2-carboxylicacid 98%
250mg
$ 49.00

Total 26 raw suppliers

Chemical Property of 6-Methyl-1H-indole-2-carboxylic acid

Chemical Property:

Vapor Pressure:1.65E-07mmHg at 25°C
Refractive Index:1.696
Boiling Point:411.5 °C at 760 mmHg
PKA:4.52±0.30(Predicted)
Flash Point:202.7 °C
PSA：53.09000
Density:1.34 g/cm³
LogP:2.17450
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:175.063328530
Heavy Atom Count:13
Complexity:217

Purity/Quality:

97% ^*data from raw suppliers

6-Methyl-1H-indole-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)C=C(N2)C(=O)O
Uses 6-Methyl-1H-indole-2-carboxylic Acid is used in preparation of heterocyclic compounds, notably indole derivatives useful in the treatment of disorders that lead to accumulation of oxalate.

Technology Process of 6-Methyl-1H-indole-2-carboxylic acid

There total 4 articles about 6-Methyl-1H-indole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95-81-8
2-chloro-5-methylaniline

: 127-17-3
2-oxo-propionic acid

: 18474-59-4
6-methyl-1H-indole-2-carboxylic acid

Guidance literature:: With potassium phosphate; magnesium sulfate; acetic acid; bis(tri-t-butylphosphine)palladium⁽⁰⁾; In N,N-dimethyl acetamide; at 140 ℃; for 24h;
DOI:10.1021/jm0490540

Reference yield:

: 103264-29-5
(4-methyl-2-nitro-phenyl)-pyruvic acid

: 18474-59-4
6-methyl-1H-indole-2-carboxylic acid

Guidance literature:: With ammonium hydroxide; iron(II) hydroxide;

Reference yield:

: 89-58-7
mononitro-p-xylene

: 18474-59-4
6-methyl-1H-indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ethanolic sodium ethylate

2: Na₂S₂O₄; aqueous NaOH

With sodium hydroxide; sodium dithionite; sodium ethanolate;
DOI:10.1021/ja01191a072