Technology Process of C26H36O5
There total 4 articles about C26H36O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(S)-4-(4-Methoxy-benzyloxy)-3-methyl-butan-2-one;
With
triethylamine; B-chlorodiisopinocampheylborane;
In
diethyl ether;
at 0 ℃;
for 2h;
Inert atmosphere;
(R)-3-(benzyloxy)hex-5-enal;
In
diethyl ether;
at -78 - 25 ℃;
Inert atmosphere;
With
dihydrogen peroxide; sodium hydroxide;
In
tetrahydrofuran; water;
at 0 - 25 ℃;
Reagent/catalyst;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1021/ol3033303
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 0.33 h / 20 °C / Inert atmosphere
2.1: triethylamine; B-chlorodiisopinocampheylborane / diethyl ether / 2 h / 0 °C / Inert atmosphere
2.2: -78 - 25 °C / Inert atmosphere
2.3: 0 - 25 °C / Inert atmosphere
With
sodium hydrogencarbonate; Dess-Martin periodane; triethylamine; B-chlorodiisopinocampheylborane;
In
diethyl ether; dichloromethane;
DOI:10.1021/ol3033303
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / mineral oil; tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
1.2: 144 h / 20 °C / Inert atmosphere
2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0 - 20 °C / pH 7 / Inert atmosphere
3.1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 0.33 h / 20 °C / Inert atmosphere
4.1: triethylamine; B-chlorodiisopinocampheylborane / diethyl ether / 2 h / 0 °C / Inert atmosphere
4.2: -78 - 25 °C / Inert atmosphere
4.3: 0 - 25 °C / Inert atmosphere
With
sodium hydride; sodium hydrogencarbonate; Dess-Martin periodane; triethylamine; B-chlorodiisopinocampheylborane; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
tetrahydrofuran; diethyl ether; dichloromethane; mineral oil;
DOI:10.1021/ol3033303