1,1-dimethylethyl {2-[({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)(hydroxy)amino]-3-phenylpropyl}carbamate

Base Information

• Chemical Name: 1,1-dimethylethyl {2-[({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)(hydroxy)amino]-3-phenylpropyl}carbamate
• CAS No.: 943324-41-2
• Molecular Formula: C₃₂H₃₁BrN₄O₆S₂
• Molecular Weight: 711.657

Synonyms:1,1-dimethylethyl {2-[({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)(hydroxy)amino]-3-phenylpropyl}carbamate

Chemical Property of 1,1-dimethylethyl {2-[({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)(hydroxy)amino]-3-phenylpropyl}carbamate

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Technology Process of 1,1-dimethylethyl {2-[({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)(hydroxy)amino]-3-phenylpropyl}carbamate

There total 1 articles about 1,1-dimethylethyl {2-[({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)(hydroxy)amino]-3-phenylpropyl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1,1-dimethylethyl {2-[[(4,5-dibromo-2-thienyl)carbonyl](hydroxy)amino]-3-phenylpropyl}carbamate (943324-39-8) → 1,1-dimethylethyl {2-[({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)(hydroxy)amino]-3-phenylpropyl}carbamate (943324-41-2)

Guidance literature:

With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 70 ℃; for 2h;

Reference yield:

1,1-dimethylethyl {2-[({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)(hydroxy)amino]-3-phenylpropyl}carbamate (943324-41-2) → C26H27BrN4O4S

Guidance literature:

With methanol; sodium hydroxide; water; at 20 ℃; for 0.5h;

upstream raw materials:

1,1-dimethylethyl {2-[[(4,5-dibromo-2-thienyl)carbonyl](hydroxy)amino]-3-phenylpropyl}carbamate

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