N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide

Base Information

Chemical Name:N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide
CAS No.:110506-36-0
Molecular Formula:C₁₂H₁₂N₂O₂S
Molecular Weight:248.305
Hs Code.:
DSSTox Substance ID:DTXSID201228988
ChEMBL ID:CHEMBL1438022
Mol file:110506-36-0.mol

Synonyms:N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide;110506-36-0;Thiophene-2-carboxylic acid (4-amino-2-methoxy-phenyl)-amide;N-(4-amino-2-methoxyphenyl)-2-thiophenecarboxamide;Cambridge id 6332315;Oprea1_632730;Oprea1_669535;MLS000061997;CHEMBL1438022;DTXSID201228988;HMS2318J09;MFCD02258051;STK090134;AKOS000108409;SDCCGMLS-0035129.P002;SMR000070858;BB 0245297;CS-0329634;AB00105360-01;SR-01000462045;SR-01000462045-1;thiophene-2-carboxylic acid (4-amino-2-methoxyphenyl)amide;Thiophene-2-carboxylic acid (4-amino-2-methoxy-phenyl)-amide;Thiophene-2-carboxylic acid (4-amino-2-methoxyphenyl)-amide;thiophene-2-carboxylic acid(4-amino-2-methoxy-phenyl)-amide

Suppliers and Price of N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Thiophene-2-carboxylic acid (4-amino-2-methoxy-phenyl)-amide
500mg
$ 199.00

Crysdot
N-(4-Amino-2-methoxyphenyl)thiophene-2-carboxamide 97%
5g
$ 853.00

Arctom
N-(4-Amino-2-methoxyphenyl)thiophene-2-carboxamide 97%
1g
$ 284.00

Arctom
N-(4-Amino-2-methoxyphenyl)thiophene-2-carboxamide 97%
5g
$ 852.00

American Custom Chemicals Corporation
THIOPHENE-2-CARBOXYLIC ACID (4-AMINO-2-METHOXY-PHENYL)-AMIDE 95.00%
500MG
$ 795.80

Total 5 raw suppliers

Chemical Property of N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide

Chemical Property:

Boiling Point:355.3±37.0 °C(Predicted)
PKA:11.65±0.70(Predicted)
Density:1.348±0.06 g/cm3(Predicted)
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:248.06194880
Heavy Atom Count:17
Complexity:275

Purity/Quality:

98%min ^*data from raw suppliers

Thiophene-2-carboxylic acid (4-amino-2-methoxy-phenyl)-amide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)N)NC(=O)C2=CC=CS2

Technology Process of N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide

There total 3 articles about N-(4-amino-2-methoxyphenyl)thiophene-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 110506-17-7
N-(2-Thenoyl)-4-nitro-o-anisidine

: 110506-36-0
Thiophene-2-carboxylic acid (4-amino-2-methoxy-phenyl)-amide

Guidance literature:: With hydrazine hydrate; nickel; In ethanol; for 2h; Heating;

Reference yield:

: 5271-67-0
2-Thiophenecarbonyl chloride

: 110506-36-0
Thiophene-2-carboxylic acid (4-amino-2-methoxy-phenyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / K₂CO₃ / acetone / 1 h / Heating

2: 63 percent / 100percent N₂H₄*H₂O / Raney nickel / ethanol / 2 h / Heating

With potassium carbonate; hydrazine hydrate; nickel; In ethanol; acetone;

Reference yield:

: 97-52-9
2-methoxy-4-nitrophenylamine

: 110506-36-0
Thiophene-2-carboxylic acid (4-amino-2-methoxy-phenyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / K₂CO₃ / acetone / 1 h / Heating

2: 63 percent / 100percent N₂H₄*H₂O / Raney nickel / ethanol / 2 h / Heating

With potassium carbonate; hydrazine hydrate; nickel; In ethanol; acetone;