Technology Process of (2R,3R,4R,5R)-1,6-bis-benzyloxy-2,5-difluorohexane-3,4-diol cyclic sulfate
There total 1 articles about (2R,3R,4R,5R)-1,6-bis-benzyloxy-2,5-difluorohexane-3,4-diol cyclic sulfate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(2R,3R,4R,5R)-1,6-bis-benzyloxy-2,5-difluorohexane-3,4-diol;
With
pyridine; thionyl chloride;
In
dichloromethane;
at 0 ℃;
for 2h;
With
sodium periodate;
ruthenium trichloride;
In
water; acetonitrile;
at 0 ℃;
for 3h;
Further stages.;
DOI:10.1002/anie.200701988
- Guidance literature:
-
(2R,3R,4R,5R)-1,6-bis-benzyloxy-2,5-difluorohexane-3,4-diol cyclic sulfate;
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran; acetonitrile;
at 0 - 20 ℃;
for 4h;
With
sulfuric acid;
In
tetrahydrofuran;
at 20 ℃;
for 17h;
Further stages.;
DOI:10.1002/anie.200701988
