12-Tridecyn-1-ol

Base Information

• Chemical Name: 12-Tridecyn-1-ol
• CAS No.: 18202-11-4
• Molecular Formula: C13H24 O
• Molecular Weight: 196.333
• Hs Code.: 2905290000
• Mol file: 18202-11-4.mol

Synonyms:12-TRIDECYN-1-OL

Chemical Property of 12-Tridecyn-1-ol

Chemical Property:

• Melting Point: 25.6°C (estimate)
• Refractive Index: 1.4575 (estimate)
• Boiling Point: 303.24°C (rough estimate)
• PKA: 15.20±0.10(Predicted)
• PSA: 20.23000
• Density: 0.7912 (estimate)
• LogP: 3.51290

Purity/Quality:

98%,99%, ^*data from raw suppliers

12-TRIDECYN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 12-Tridecyn-1-ol

There total 22 articles about 12-Tridecyn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

13-<(tetrahydropyran-2'-yl)oxy>tridecan-1-yne (56772-54-4) → tridec-12-yn-1-ol (18202-11-4)

Guidance literature:

With hydrogenchloride; In ethanol; for 16h; Heating;

Reference yield: 87.0%

tridec-2-yn-1-ol (51887-25-3) → tridec-12-yn-1-ol (18202-11-4)

Guidance literature:

With sodium hydride; Trimethylenediamine; In Cyclopentane;

DOI:10.1016/S0040-4039(97)00285-2

Reference yield: 50.0%

1-Bromo-11-hydroxyundecane (1611-56-9) + lithium acetylide-ethylenediamine complex (1216963-74-4) → tridec-12-yn-1-ol (18202-11-4)

Guidance literature:

In dimethyl sulfoxide; at 8 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1021/jacs.5b11892

upstream raw materials:

13-<(tetrahydropyran-2'-yl)oxy>tridecan-1-yne

1-Bromo-11-hydroxyundecane

lithium trimethylsilylacetylenide

tridec-2-yn-1-ol

Downstream raw materials:

C₃₆H₅₈O₃

C₃₆H₅₆O₃

13-Bromo-1-tridecene

ω-tridecyn-1-oic acid

Refernces

• 1、 Snider, Barry B.,Shi, Bo. "Synthesis of pyrinodemins A and B. Assignment of the double bond position of pyrinodemin A". . p. 1639 - 1642. Retrieved 2001.
• 2、 Romuald, Camille,Cazals, Guillaume,Enjalbal, Christine,Coutrot, Frédéric. "Straightforward synthesis of a double-lasso macrocycle from a nonsymmetrical [c2]daisy chain". . p. 184 - 187. Retrieved 2013.
• 3、 -. "LIPOSOME FORMULATION". Page/Page column 18. . Retrieved 2020/12/30.
• 4、 Shimada, Kazuaki,Sugawara, Ayako,Korenaga, Toshinobu,Kawashima, Hideki. "Total Synthesis and Structural Elucidation of Two Unusual Non-Methylene-Interrupted Fatty Acids in Ovaries of the Limpet Cellana toreuma". . p. 1019 - 1032. Retrieved 2017/10/07.