O-Acetyl-4-nitrocatechol

Base Information

• Chemical Name: O-Acetyl-4-nitrocatechol
• CAS No.: 53602-63-4
• Molecular Formula: C₈H₇NO₅
• Molecular Weight: 197.147
• Mol file: 53602-63-4.mol

Synonyms:O-Acetyl-4-nitrocatechol

Chemical Property of O-Acetyl-4-nitrocatechol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-Acetyl-4-nitrocatechol

There total 5 articles about O-Acetyl-4-nitrocatechol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-Ethoxy-2-methyl(5-nitrobenzo)-1,3-dioxolane (77400-20-5) → O-Acetyl-4-nitrocatechol (53602-63-4)

Guidance literature:

With boron trifluoride diethyl etherate; sodium iodide; In dichloromethane; acetone; at 0 ℃; for 0.0833333h;

DOI:10.1021/jo00328a020

Reference yield: 80.0%

2-Methyl-2-(2,2,2-trichloroethoxy)(4-nitrobenzo)-1,3-dioxolane (77400-27-2) → O-Acetyl-4-nitrocatechol (53602-63-4)

Guidance literature:

With sulfuric acid; In water; acetone;

DOI:10.1021/jo00328a020

Reference yield:

1,2-dihydroxy-4-nitrobenzene (3316-09-4) → O-Acetyl-4-nitrocatechol (53602-63-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / sat. solution of HCl/EtOH

2: 27 percent / conc. sulfuric acid / 3 h / 120 °C

3: 80 percent / sulfuric acid / acetone; H₂O

With hydrogenchloride; ethanol; sulfuric acid; In water; acetone;

DOI:10.1021/jo00328a020

upstream raw materials:

2-acetoxyphenol

2-Ethoxy-2-methyl(5-nitrobenzo)-1,3-dioxolane

2-Methyl-2-(2,2,2-trichloroethoxy)(4-nitrobenzo)-1,3-dioxolane

1,2-dihydroxy-4-nitrobenzene

Downstream raw materials:

1,2-dihydroxy-4-nitrobenzene