Angiotensin II, ala(8)-

Base Information

• Chemical Name: Angiotensin II, ala(8)-
• CAS No.: 18197-01-8
• Molecular Formula: C₄₄H₆₇N₁₃O₁₂
• Molecular Weight: 970.096
• DSSTox Substance ID: DTXSID20171221
• ChEMBL ID: CHEMBL2392353
• Mol file: 18197-01-8.mol

Synonyms:8-Ala-angiotensin II;8-alanine-angiotensin II;angiotensin II, Ala(8)-;angiotensin II, alanine(8)-

Chemical Property of Angiotensin II, ala(8)-

Chemical Property:

• Refractive Index: 1.663
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 427.28000
• Density: 1.47g/cm³
• LogP: 4.54310
• XLogP3: -3.3
• Hydrogen Bond Donor Count: 13
• Hydrogen Bond Acceptor Count: 15
• Rotatable Bond Count: 27
• Exact Mass: 969.50321462
• Heavy Atom Count: 69
• Complexity: 1830

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(C)C(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N
• Isomeric SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)O)N

Technology Process of Angiotensin II, ala(8)-

There total 1 articles about Angiotensin II, ala(8)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Asp-Arg-Val-Tyr-Val-His-Pro-Ala (18197-01-8,52739-43-2)

Guidance literature:

Boc-Asp(OCH2Ph)-Arg(NO2)-Val-Tyr(OCH2Ph)-Ile-His(CH2Ph)-Pro-D-Ala (Merrifield Festphasen-Synthese) 1) in Trifluoressigsaeure + HBr (Gas) 2) Me/Eg/W + H2 (Pd);

DOI:10.1139/o74-018