4-benzyl-2,2-dimethyltetrahydrofuran

Base Information

• Chemical Name: 4-benzyl-2,2-dimethyltetrahydrofuran
• CAS No.: 97677-87-7
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.285
• Mol file: 97677-87-7.mol

Synonyms:4-benzyl-2,2-dimethyltetrahydrofuran

Chemical Property of 4-benzyl-2,2-dimethyltetrahydrofuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-benzyl-2,2-dimethyltetrahydrofuran

There total 6 articles about 4-benzyl-2,2-dimethyltetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C14H20O → 4-benzyl-2,2-dimethyltetrahydrofuran (97677-87-7)

Guidance literature:

With aluminium(III) triflate; In dichloromethane; at 40 ℃; for 1h;

DOI:10.1002/chem.200501478

Reference yield: 87.0%

2-Benzyl-4-methyl-pentane-1,4-diol (97677-85-5) → 4-benzyl-2,2-dimethyltetrahydrofuran (97677-87-7)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; at 220 ℃; for 10h;

DOI:10.1016/S0040-4039(00)98535-6

Reference yield:

2-Benzyl-4-oxopentanoic acid (6049-46-3) → 4-benzyl-2,2-dimethyltetrahydrofuran (97677-87-7)

Guidance literature:

Multi-step reaction with 4 steps

2: H⁺ / Heating

3: AlH₄Li

4: 87 percent / hexamethylphosphoramide / 10 h / 220 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium aluminium tetrahydride; hydrogen cation;

DOI:10.1016/S0040-4039(00)98535-6

upstream raw materials:

2-Benzyl-4-methyl-pentane-1,4-diol

2-Benzyl-4-oxopentanoic acid

3-benzyl-5,5-dimethyltetrahydrofuran-2-one

2-Benzyl-4-hydroxy-4-methyl-pentanoic acid