Technology Process of 3-(triphenylplumbyl)-all-trans-1,5,9-cyclododecatriene
There total 1 articles about 3-(triphenylplumbyl)-all-trans-1,5,9-cyclododecatriene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
water; lithium;
In
tetrahydrofuran;
under N2; addn. of Li wire to a suspn. of ClPbPh3 in THF at room temp.;stirring for 15 h; filtration; addn. of ttt-3-Br-CDT in THF to the cooled (0°C) black soln.; stirring at room temp. for 50 h; addn. of H2O;; extg. (ether, 3 times); washing (water); drying (MgSO4); evapn. of solvent; dissolving (acetone); filtration from (C6H5)4Pb; evapn. of solvent (vac.); dissolving of the light yellow oil in boiling ethanol; crystn. on cooling (ice-box); elem. anal.;;
- Guidance literature:
-
With
1-bromo-butane; water;
In
tetrahydrofuran;
byproducts: all-trans-1,5,9-cyclododecatriene; N2 atmosphere; addn. of PhLi to the triphenylplumbyl compd. in THF at -65°C; stirring at -65°C for 0.5 h; addn. of 1-bromobutane to the light yellow soln.; warming to room temp.; hydrolysis with water;; extg. (ether); washing (water); drying; evapn. of solvent; dissolution in acetone; filtration of Pb(C6H5)4;;
- Guidance literature:
-
With
phenyllithium;
In
diethyl ether; benzene;
at -65 ℃;
for 0.5h;
