phenylmethyl 3-[(4-phenylmethoxy)phenyl]propanoate

Base Information

• Chemical Name: phenylmethyl 3-[(4-phenylmethoxy)phenyl]propanoate
• CAS No.: 129967-35-7
• Molecular Formula: C₂₃H₂₂O₃
• Molecular Weight: 346.426
• Mol file: 129967-35-7.mol

Synonyms:phenylmethyl 3-[(4-phenylmethoxy)phenyl]propanoate

Chemical Property of phenylmethyl 3-[(4-phenylmethoxy)phenyl]propanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of phenylmethyl 3-[(4-phenylmethoxy)phenyl]propanoate

There total 2 articles about phenylmethyl 3-[(4-phenylmethoxy)phenyl]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-(2-hydroxyphenyl)propionic acid (495-78-3) + benzyl chloride (100-44-7) → phenylmethyl 3-[(4-phenylmethoxy)phenyl]propanoate (129967-35-7)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 12h; Heating;

DOI:10.1021/jo00310a019

Reference yield:

o-Coumaric acid (614-60-8) → phenylmethyl 3-[(4-phenylmethoxy)phenyl]propanoate (129967-35-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / hydrogen / Pd/C / ethanol / 1.5 h

2: 75 percent / K₂CO₃, KI / acetone / 12 h / Heating

With hydrogen; potassium carbonate; potassium iodide; palladium on activated charcoal; In ethanol; acetone;

DOI:10.1021/jo00310a019

Reference yield: 80.0%

phenylmethyl 3-[(4-phenylmethoxy)phenyl]propanoate (129967-35-7) → 3-(2'-(Benzyloxy)phenyl)propionic Acid (48179-00-6)

Guidance literature:

With sodium hydroxide; In methanol; for 12h;

DOI:10.1021/jo00310a019

upstream raw materials:

3-(2-hydroxyphenyl)propionic acid

benzyl chloride

o-Coumaric acid

Downstream raw materials:

3-(2'-(Benzyloxy)phenyl)propionic Acid

2-(3-hydroxypropyl)phenol

4-Methoxyaniline 3-(2'-Hydroxyphenyl)propionic Acid Amide

4-Methoxyaniline 3-(2'-(Benzyloxy)phenyl)propionic Acid Amide